Ryan has four sisters, Demi, Sasha, Octavia and Kayla a little brother who is also a professional boxer named Sean. His parents are Henry and Lisa Garcia. His parents were actively involved in his amateur career. They continue to assist Ryan with his professional career as his father remains one of his trainers and his mother works as his Personal Administrative Assistant for commercial projects. Ryan Garcia was challenged to a boxing bout by Tyler “Wood” Capron, but rejected the bout.
Although being American by birth and nationality, Garcia often incorporates his Mexican heritage into his persona. He often carries both the U.S. and Mexican flag into the ring and frequently wears red, white, and blue colors. He is promoted by Golden Boy Boxing. Though he doesn’t speak Spanish, he is currently trained by Eddy Reynoso, who also trains Saul "Canelo" Alvarez. However, his father Henry Garcia translates as he remains second assistant on the training team.