São Jorge dos Órgãos is a settlement in the central part of the island of Santiago, Cape Verde. Its 2010 population was 6. It is situated 4 km southeast of Picos and its elevation is 319 meters. It is part of the São Lourenço dos Órgãos municipality.
It is home to the Jardim Botânico (Botanical Garden), the only one in Cape Verde. There is also an experimental station of the Instituto Nacional de Investigação e Desenvolvimento Agrário, an agricultural research institute funded by the Department of Rural Development. Also there is a secondary school or gymnasium named Carlos Alberto Gonçalves, along with the botanical garden forms a part of the University of Cape Verde.