The main historical culture of Sédhiou came from the Mandinka people, but many populations are located in the area nowadays.
It is the capital of Sédhiou Region.
In 1983, 13,212 inhabitants lived in the town, rising to 18,465 in 2002. At the 2013 census Sédhiou had a population of 24,213.
- "Senegal: Regions, Major Cities, Urban Communes & Urban Agglomerations - Population Statistics in Maps and Charts". www.citypopulation.de. Retrieved 25 September 2017.
- (in French) City web site
- (in French) Présentation of Sédhiou on Les Ulis official web site