SA-4503

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SA-4503
SA 4503.png
Names
IUPAC name
1-[2-(3,4-Dimethoxyphenyl)ethyl]-4-(3-phenylpropyl)piperazine
Identifiers
3D model (Jmol)
Properties
C23H32N2O2
Molar mass 368.52 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

SA 4503 is a sigma receptor agonist.[1][2][3]

References[edit]

  1. ^ Matsuno K, Nakazawa M, Okamoto K, Kawashima Y, Mita S (1996). "Binding properties of SA4503, a novel and selective sigma 1 receptor agonist". European Journal of Pharmacology. 306 (1–3): 271–9. doi:10.1016/0014-2999(96)00201-4. PMID 8813641. 
  2. ^ Skuza G, Rogóz Z (2006). "The synergistic effect of selective sigma receptor agonists and uncompetitive NMDA receptor antagonists in the forced swim test in rats". J. Physiol. Pharmacol. 57 (2): 217–29. PMID 16845227. 
  3. ^ Xu R, Lord SA, Peterson RM, Fergason-Cantrell EA, Lever JR, Lever SZ (January 2015). "Ether modifications to 1-[2-(3,4-dimethoxyphenyl)ethyl]-4-(3-phenylpropyl)piperazine (SA4503): effects on binding affinity and selectivity for sigma receptors and monoamine transporters.". Bioorganic & Medicinal Chemistry. 23 (1): 222–230. doi:10.1016/j.bmc.2014.11.007. PMC 4274187Freely accessible. PMID 25468036. 

External links[edit]