SDB-006

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SDB-006
SDB-006 structure.png
Systematic (IUPAC) name
N-benzyl-1-pentyl-1H-indole-3-carboxamide
Clinical data
Legal status
Identifiers
CAS Registry Number 695213-59-3 YesY
PubChem CID: 2227769
ChemSpider 1665835
Chemical data
Formula C21H24N2O
Molecular mass 320.43 g/mol

SDB-006 is a drug that acts as a potent agonist for the cannabinoid receptors, with an EC50 of 19 nM for human CB2 receptors, and 134 nM for human CB1 receptors.[1] It was discovered during research into the related compound SDB-001 which had been sold illicitly as "2NE1".[2]

See also[edit]

References[edit]

  1. ^ Banister, S. D.; Stuart, J.; Kevin, R. C.; Edington, A.; Longworth, M.; Wilkinson, S. M.; Beinat, C.; Buchanan, A. S.; Hibbs, D. E.; Glass, M.; Connor, M.; McGregor, I. S.; Kassiou, M. (2015). "Effects of Bioisosteric Fluorine in Synthetic Cannabinoid Designer Drugs JWH-018, AM-2201, UR-144, XLR-11, PB-22, 5F-PB-22, APICA, and STS-135". ACS Chemical Neuroscience: 150508124201002. doi:10.1021/acschemneuro.5b00107.  edit
  2. ^ Banister, S. D.; Wilkinson, S. M.; Longworth, M.; Stuart, J.; Apetz, N.; English, K.; Brooker, L.; Goebel, C.; Hibbs, D. E.; Glass, M.; Connor, M.; McGregor, I. S.; Kassiou, M. (2013). "The synthesis and pharmacological evaluation of adamantane-derived indoles: Novel cannabimimetic drugs of abuse". ACS Chemical Neuroscience 4 (7): 130403084729007. doi:10.1021/cn400035r.  edit