SEMA4B

SEMA4B
Identifiers
Aliases	SEMA4B, SEMAC, SemC, semaphorin 4B
External IDs	OMIM: 617029; MGI: 107559; HomoloGene: 8426; GeneCards: SEMA4B; OMA:SEMA4B - orthologs
Gene location (Human)
Chr.	Chromosome 15 (human)
End	90,229,679 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	79,876,275 bp
RNA expression pattern
	Top expressed in
	mucosa of ileum; ; mucosa of esophagus; ; secondary oocyte; ; muscle layer of sigmoid colon; ; olfactory zone of nasal mucosa; ; gums; ; vagina; ; transverse colon; ; gingival epithelium; ; right lobe of thyroid gland;
	Top expressed in
	cumulus cell; ; external carotid artery; ; submandibular gland; ; ciliary body; ; internal carotid artery; ; lumbar spinal ganglion; ; lip; ; Rostral migratory stream; ; yolk sac; ; blood;
	More reference expression data
	n/a
Gene ontology
Molecular function	neuropilin binding; semaphorin receptor binding; chemorepellent activity;
Cellular component	integral component of membrane; membrane; extracellular space; plasma membrane; integral component of plasma membrane;
Biological process	multicellular organism development; cell differentiation; nervous system development; negative chemotaxis; neural crest cell migration; positive regulation of cell migration; negative regulation of axon extension involved in axon guidance; semaphorin-plexin signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	10509
	20352
	ENSG00000185033
	ENSMUSG00000030539
	Q9NPR2
	Q62179
NM_020210; NM_198925; NM_001324029; NM_001324030; NM_001324031;
	NM_001324032; NM_001324034; NM_001393916
	NM_013659; NM_001360135
NP_001310958; NP_001310959; NP_001310960; NP_001310961; NP_001310962;
	NP_001310963; NP_064595; NP_945119
	NP_038687; NP_001347064
	Wikidata
View/Edit Human	View/Edit Mouse

Semaphorin-4B is a protein that in humans is encoded by the SEMA4B gene.^[5]^[6]

Template:PBB Summary

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000185033 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000030539 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Puschel AW, Adams RH, Betz H (Jun 1995). "Murine semaphorin D/collapsin is a member of a diverse gene family and creates domains inhibitory for axonal extension". Neuron. 14 (5): 941–8. doi:10.1016/0896-6273(95)90332-1. PMID 7748561.
^ "Entrez Gene: SEMA4B sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B".

References

Further reading