SEMA4G

From Wikipedia, the free encyclopedia
Jump to: navigation, search
SEMA4G
Identifiers
Aliases SEMA4G
External IDs MGI: 1347047 HomoloGene: 22682 GeneCards: SEMA4G
RNA expression pattern
PBB GE SEMA4G 219194 at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001203244
NM_017893

NM_011976

RefSeq (protein)

NP_001190173
NP_060363

NP_036106.1
NP_036106

Location (UCSC) Chr 10: 100.97 – 100.99 Mb Chr 19: 44.99 – 45 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Semaphorin-4G is a protein that in humans is encoded by the SEMA4G gene.[3]

Semaphorins are a large family of conserved secreted and membrane associated proteins which possess a semaphorin (Sema) domain and a PSI domain (found in plexins, semaphorins and integrins) in the N-terminal extracellular portion. Based on sequence and structural similarities, semaphorins are put into eight classes: invertebrates contain classes 1 and 2, viruses have class V, and vertebrates contain classes 3-7. Semaphorins serve as axon guidance ligands via multimeric receptor complexes, some (if not all) containing plexin proteins. This gene encodes a class 4 semaphorin. This gene and the gene for mitochondrial ribosomal protein L43 overlap at map location 10q24.31 and are transcribed in opposite directions.[3]

References[edit]

Further reading[edit]