SENP3

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SENP3
Identifiers
Aliases SENP3, SMT3IP1, SSP3, Ulp1, SUMO1/sentrin/SMT3 specific peptidase 3
External IDs MGI: 2158736 HomoloGene: 9236 GeneCards: SENP3
RNA expression pattern
PBB GE SENP3 215113 s at fs.png

PBB GE SENP3 203871 at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_015670

NM_001163571
NM_030702

RefSeq (protein)

NP_056485

NP_001157043.1
NP_109627.3
NP_001157043
NP_109627

Location (UCSC) Chr 17: 7.56 – 7.57 Mb Chr 11: 69.67 – 69.68 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

SUMO1/sentrin/SMT3 specific peptidase 3, also known as SENP3, is a protein which in humans is encoded by the SENP3 gene.[3][4]

SENP3 together with SENP5, belongs to the Ulp1 branch in yeast and localize to nucleolus through B23/NPM1. SENP3 is associated and regulated by B23/nucleophosmin/NPM1 and involved in the regulation of ribosome biogenesis. SENP3 may be regulated by Arf-Mdm2-p53 pathway.[5]

Further reading[edit]


References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Yeh ET, Gong L, Kamitani T (May 2000). "Ubiquitin-like proteins: new wines in new bottles". Gene. 248 (1–2): 1–14. doi:10.1016/S0378-1119(00)00139-6. PMID 10806345. 
  4. ^ Wiemann S, Weil B, Wellenreuther R, Gassenhuber J, Glassl S, Ansorge W, Böcher M, Blöcker H, Bauersachs S, Blum H, Lauber J, Düsterhöft A, Beyer A, Köhrer K, Strack N, Mewes HW, Ottenwälder B, Obermaier B, Tampe J, Heubner D, Wambutt R, Korn B, Klein M, Poustka A (March 2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072Freely accessible. PMID 11230166. 
  5. ^ "Entrez Gene: SENP3 SUMO1/sentrin/SMT3 specific peptidase 3".