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AliasesSERPINB9, CAP-3, CAP3, PI-9, PI9, serpin family B member 9
External IDsMGI: 106603 HomoloGene: 37888 GeneCards: SERPINB9
Gene location (Human)
Chromosome 6 (human)
Chr.Chromosome 6 (human)[1]
Chromosome 6 (human)
Genomic location for SERPINB9
Genomic location for SERPINB9
Band6p25.2Start2,887,266 bp[1]
End2,903,280 bp[1]
RNA expression pattern
PBB GE SERPINB9 209722 s at fs.png

PBB GE SERPINB9 209723 at fs.png
More reference expression data
RefSeq (mRNA)



RefSeq (protein)



Location (UCSC)Chr 6: 2.89 – 2.9 MbChr 13: 33 – 33.02 Mb
PubMed search[3][4]
View/Edit HumanView/Edit Mouse

Serpin B9 is a protein that in humans is encoded by the SERPINB9 gene.[5][6][7]

PI9 belongs to the large superfamily of serine proteinase inhibitors (serpins), which bind to and inactivate serine proteinases. These interactions are involved in many cellular processes, including coagulation, fibrinolysis, complement fixation, matrix remodeling, and apoptosis (Sprecher et al., 1995).[supplied by OMIM][7]

See also[edit]


  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000170542 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000045827 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:".
  4. ^ "Mouse PubMed Reference:".
  5. ^ Sprecher CA, Morgenstern KA, Mathewes S, Dahlen JR, Schrader SK, Foster DC, Kisiel W (Jan 1996). "Molecular cloning, expression, and partial characterization of two novel members of the ovalbumin family of serine proteinase inhibitors". J Biol Chem. 270 (50): 29854–61. doi:10.1074/jbc.270.50.29854. PMID 8530382.
  6. ^ Sun J, Stephens R, Mirza G, Kanai H, Ragoussis J, Bird PI (Feb 1999). "A serpin gene cluster on human chromosome 6p25 contains PI6, PI9 and ELANH2 which have a common structure almost identical to the 18q21 ovalbumin serpin genes". Cytogenet Cell Genet. 82 (3–4): 273–7. doi:10.1159/000015118. PMID 9858835.
  7. ^ a b "Entrez Gene: SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9".

Further reading[edit]

External links[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.