SGK2

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SGK2
Identifiers
AliasesSGK2, H-dJ138B7.2, serine/threonine kinase 2
External IDsMGI: 1351318 HomoloGene: 8446 GeneCards: SGK2
Gene location (Human)
Chromosome 20 (human)
Chr.Chromosome 20 (human)[1]
Chromosome 20 (human)
Genomic location for SGK2
Genomic location for SGK2
Band20q13.12Start43,558,968 bp[1]
End43,588,237 bp[1]
RNA expression pattern
PBB GE SGK2 220357 s at fs.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_170693
NM_001199264
NM_016276

NM_001291152
NM_001291154
NM_013731

RefSeq (protein)

NP_001186193
NP_057360
NP_733794

NP_001278081
NP_001278083
NP_038759

Location (UCSC)Chr 20: 43.56 – 43.59 MbChr 2: 162.99 – 163.01 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Serine/threonine-protein kinase Sgk2 is an enzyme that in humans is encoded by the SGK2 gene.[5][6]

This gene encodes a serine/threonine protein kinase. Although this gene product is similar to serum- and glucocorticoid-induced protein kinase (SGK), this gene is not induced by serum or glucocorticoids. This gene is induced in response to signals that activate phosphatidylinositol 3-kinase (PI3K), which is also true for SGK. Two alternate transcripts encoding two different isoforms have been described.[6]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000101049 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000017868 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:".
  4. ^ "Mouse PubMed Reference:".
  5. ^ Kobayashi T, Deak M, Morrice N, Cohen P (Jan 2000). "Characterization of the structure and regulation of two novel isoforms of serum- and glucocorticoid-induced protein kinase". Biochem J. 344 (1): 189–97. doi:10.1042/0264-6021:3440189. PMC 1220630. PMID 10548550.
  6. ^ a b "Entrez Gene: SGK2 serum/glucocorticoid regulated kinase 2".

Further reading[edit]

External links[edit]