SH3GL3

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SH3GL3
Protein SH3GL3 PDB 2ew3.png
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases SH3GL3, CNSA3, EEN-B2, HsT19371, SH3D2C, SH3P13, SH3 domain containing GRB2 like endophilin A3
External IDs MGI: 700011 HomoloGene: 37723 GeneCards: 6457
RNA expression pattern
PBB GE SH3GL3 205637 s at tn.png

PBB GE SH3GL3 gnf1h02191 at tn.png

PBB GE SH3GL3 gnf1h02192 x at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001277954
NM_001277955
NM_017400

RefSeq (protein)

NP_001288037.1
NP_001288038.1
NP_003018.3

NP_059096.3

Location (UCSC) Chr 15: 83.45 – 83.62 Mb n/a
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Endophilin-A3 is a protein that in humans is encoded by the SH3GL3 gene.[1][2]

Interactions[edit]

SH3GL3 has been shown to interact with Huntingtin[3] and SH3KBP1.[4]

References[edit]

  1. ^ Giachino C, Lantelme E, Lanzetti L, Saccone S, Bella Valle G, Migone N (July 1997). "A novel SH3-containing human gene family preferentially expressed in the central nervous system". Genomics 41 (3): 427–34. doi:10.1006/geno.1997.4645. PMID 9169142. 
  2. ^ "Entrez Gene: SH3GL3 SH3-domain GRB2-like 3". 
  3. ^ Sittler A, Wälter S, Wedemeyer N, Hasenbank R, Scherzinger E, Eickhoff H, Bates GP, Lehrach H, Wanker EE (October 1998). "SH3GL3 associates with the Huntingtin exon 1 protein and promotes the formation of polygln-containing protein aggregates". Mol. Cell 2 (4): 427–36. doi:10.1016/S1097-2765(00)80142-2. PMID 9809064. 
  4. ^ Petrelli A, Gilestro GF, Lanzardo S, Comoglio PM, Migone N, Giordano S (March 2002). "The endophilin-CIN85-Cbl complex mediates ligand-dependent downregulation of c-Met". Nature 416 (6877): 187–90. doi:10.1038/416187a. PMID 11894096. 

Further reading[edit]