SLAMF8

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SLAMF8
Identifiers
Aliases SLAMF8, BLAME, CD353, SBBI42, SLAM family member 8
External IDs MGI: 1921998 HomoloGene: 10589 GeneCards: SLAMF8
RNA expression pattern
PBB GE SLAMF8 219386 s at fs.png

PBB GE SLAMF8 219385 at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_020125
NM_001330741

NM_029084

RefSeq (protein)

NP_001317670
NP_064510

NP_083360.2
NP_083360

Location (UCSC) Chr 1: 159.83 – 159.84 Mb Chr 1: 172.58 – 172.59 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

SLAM family member 8 is a protein that in humans is encoded by the SLAMF8 gene.[3][4]

Function[edit]

This gene encodes a member of the CD2 family of cell surface proteins involved in lymphocyte activation. These proteins are characterized by Ig domains. This protein is expressed in lymphoid tissues, and studies of a similar protein in mouse suggest that it may function during B cell lineage commitment. The gene is found in a region of chromosome 1 containing many CD2 genes.[4]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Kingsbury GA, Feeney LA, Nong Y, Calandra SA, Murphy CJ, Corcoran JM, Wang Y, Prabhu Das MR, Busfield SJ, Fraser CC, Villeval JL (May 2001). "Cloning, expression, and function of BLAME, a novel member of the CD2 family". Journal of Immunology. 166 (9): 5675–80. doi:10.4049/jimmunol.166.9.5675. PMID 11313408. 
  4. ^ a b "Entrez Gene: SLAMF8 SLAM family member 8". 

Further reading[edit]