SLC17A3

From Wikipedia, the free encyclopedia
Jump to navigation Jump to search
SLC17A3
Identifiers
AliasesSLC17A3, NPT4, GOUT4, UAQTL4, solute carrier family 17 member 3
External IDsMGI: 2389216 HomoloGene: 21319 GeneCards: SLC17A3
Gene location (Human)
Chromosome 6 (human)
Chr.Chromosome 6 (human)[1]
Chromosome 6 (human)
Genomic location for SLC17A3
Genomic location for SLC17A3
Band6p22.2Start25,833,066 bp[1]
End25,882,286 bp[1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_006632
NM_001098486

NM_001164743
NM_134069

RefSeq (protein)

NP_001091956
NP_006623

n/a

Location (UCSC)Chr 6: 25.83 – 25.88 MbChr 13: 23.84 – 23.86 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Solute carrier family 17 (organic anion transporter), member 3 is a protein that in humans is encoded by the SLC17A3 gene.[5]

Function[edit]

The protein encoded by this gene is a voltage-driven transporter that excretes intracellular urate and organic anions from the blood into renal tubule cells. Two transcript variants encoding different isoforms have been found for this gene. The longer isoform is a plasma membrane protein with transporter activity while the shorter isoform localizes to the endoplasmic reticulum.[5]

See also[edit]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000124564 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000036083 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:".
  4. ^ "Mouse PubMed Reference:".
  5. ^ a b "Entrez Gene: Solute carrier family 17 (organic anion transporter), member 3".

Further reading[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.