SLC17A3

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Solute carrier family 17 (organic anion transporter), member 3
Identifiers
Symbols SLC17A3 ; NPT4
External IDs OMIM611034 HomoloGene21319 GeneCards: SLC17A3 Gene
Orthologs
Species Human Mouse
Entrez 10786 105355
Ensembl ENSG00000124564 ENSMUSG00000036083
UniProt O00476 n/a
RefSeq (mRNA) NM_001098486 NM_001164743
RefSeq (protein) NP_001091956 NP_001158215
Location (UCSC) Chr 6:
25.83 – 25.88 Mb
Chr 13:
23.84 – 23.86 Mb
PubMed search [1] [2]

Solute carrier family 17 (organic anion transporter), member 3 is a protein that in humans is encoded by the SLC17A3 gene.[1]

Function[edit]

The protein encoded by this gene is a voltage-driven transporter that excretes intracellular urate and organic anions from the blood into renal tubule cells. Two transcript variants encoding different isoforms have been found for this gene. The longer isoform is a plasma membrane protein with transporter activity while the shorter isoform localizes to the endoplasmic reticulum.[1]

See also[edit]

References[edit]

Further reading[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.