Neutral amino acid transporter A

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SLC1A4
Identifiers
AliasesSLC1A4, ASCT1, SATT, SPATCCM, solute carrier family 1 member 4
External IDsOMIM: 600229 MGI: 2135601 HomoloGene: 20655 GeneCards: SLC1A4
Gene location (Human)
Chromosome 2 (human)
Chr.Chromosome 2 (human)[1]
Chromosome 2 (human)
Genomic location for SLC1A4
Genomic location for SLC1A4
Band2p14Start64,988,477 bp[1]
End65,023,865 bp[1]
RNA expression pattern
PBB GE SLC1A4 209610 s at fs.png

PBB GE SLC1A4 212810 s at fs.png

PBB GE SLC1A4 209611 s at fs.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001135581
NM_001193493
NM_003038
NM_001348406
NM_001348407

NM_018861

RefSeq (protein)

NP_001180422
NP_003029
NP_001335335
NP_001335336

NP_061349

Location (UCSC)Chr 2: 64.99 – 65.02 MbChr 11: 20.3 – 20.33 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Neutral amino acid transporter A is a protein that in humans is encoded by the SLC1A4 gene.[5][6][7]

In melanocytic cells SLC1A4 gene expression may be regulated by MITF.[8]

See also[edit]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000115902 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000020142 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Hofmann K, Duker M, Fink T, Lichter P, Stoffel W (Apr 1995). "Human neutral amino acid transporter ASCT1: structure of the gene (SLC1A4) and localization to chromosome 2p13-p15". Genomics. 24 (1): 20–6. doi:10.1006/geno.1994.1577. PMID 7896285.
  6. ^ Zerangue N, Kavanaugh MP (Dec 1996). "ASCT-1 is a neutral amino acid exchanger with chloride channel activity". J Biol Chem. 271 (45): 27991–4. doi:10.1074/jbc.271.45.27991. PMID 8910405.
  7. ^ "Entrez Gene: SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4".
  8. ^ Hoek KS, Schlegel NC, Eichhoff OM, et al. (2008). "Novel MITF targets identified using a two-step DNA microarray strategy". Pigment Cell Melanoma Res. 21 (6): 665–76. doi:10.1111/j.1755-148X.2008.00505.x. PMID 19067971.

Further reading[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.