SLC22A7

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SLC22A7
Identifiers
Aliases SLC22A7, NLT, OAT2, solute carrier family 22 member 7, hOAT11
External IDs MGI: 1859559 HomoloGene: 21328 GeneCards: SLC22A7
Gene location (Human)
Chromosome 6 (human)
Chr. Chromosome 6 (human)[1]
Chromosome 6 (human)
Genomic location for SLC22A7
Genomic location for SLC22A7
Band 6p21.1 Start 43,295,694 bp[1]
End 43,305,538 bp[1]
RNA expression pattern
PBB GE SLC22A7 221662 s at fs.png

PBB GE SLC22A7 220554 at fs.png

PBB GE SLC22A7 221661 at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_006672
NM_153320

NM_144856

RefSeq (protein)

NP_006663
NP_696961

NP_659105

Location (UCSC) Chr 6: 43.3 – 43.31 Mb Chr 6: 46.43 – 46.44 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Solute carrier family 22 member 7 is a protein that in humans is encoded by the SLC22A7 gene.[5][6][7]

The protein encoded by this gene is involved in the sodium-independent transport and excretion of organic anions, some of which are potentially toxic. The encoded protein is an integral membrane protein and appears to be localized to the basolateral membrane of the kidney. Alternatively spliced transcript variants encoding different isoforms have been described.[7]

Interactive pathway map[edit]

Click on genes, proteins and metabolites below to link to respective articles.[§ 1]

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FluoropyrimidineActivity_WP1601 go to article go to article go to article go to pathway article go to pathway article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to PubChem Compound go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to pathway article go to pathway article go to article go to article go to article go to article go to article go to WikiPathways go to article go to article go to article go to article go to article go to article go to article go to article go to article
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FluoropyrimidineActivity_WP1601 go to article go to article go to article go to pathway article go to pathway article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to PubChem Compound go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to pathway article go to pathway article go to article go to article go to article go to article go to article go to WikiPathways go to article go to article go to article go to article go to article go to article go to article go to article go to article
|{{{bSize}}}px|alt=Fluorouracil (5-FU) Activity edit]]
Fluorouracil (5-FU) Activity edit
  1. ^ The interactive pathway map can be edited at WikiPathways: "FluoropyrimidineActivity_WP1601". 

See also[edit]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000137204 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000067144 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". 
  4. ^ "Mouse PubMed Reference:". 
  5. ^ Sekine T, Cha SH, Tsuda M, Apiwattanakul N, Nakajima N, Kanai Y, Endou H (Jul 1998). "Identification of multispecific organic anion transporter 2 expressed predominantly in the liver". FEBS Lett. 429 (2): 179–82. doi:10.1016/S0014-5793(98)00585-7. PMID 9650585. 
  6. ^ Kok LD, Siu SS, Fung KP, Tsui SK, Lee CY, Waye MM (Jun 2000). "Assignment of liver-specific organic anion transporter (SLC22A7) to human chromosome 6 bands p21.2→p21.1 using radiation hybrids". Cytogenet Cell Genet. 88 (1–2): 76–7. doi:10.1159/000015489. PMID 10773670. 
  7. ^ a b "Entrez Gene: SLC22A7 solute carrier family 22 (organic anion transporter), member 7". 

Further reading[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.