SLC23A2

From Wikipedia, the free encyclopedia
Jump to navigation Jump to search
SLC23A2
Identifiers
AliasesSLC23A2, NBTL1, SLC23A1, SVCT2, YSPL2, hSVCT2, solute carrier family 23 member 2
External IDsMGI: 1859682 HomoloGene: 68440 GeneCards: SLC23A2
Gene location (Human)
Chromosome 20 (human)
Chr.Chromosome 20 (human)[1]
Chromosome 20 (human)
Genomic location for SLC23A2
Genomic location for SLC23A2
Band20p13Start4,852,356 bp[1]
End5,010,293 bp[1]
RNA expression pattern
PBB GE SLC23A2 211572 s at fs.png

PBB GE SLC23A2 209236 at fs.png

PBB GE SLC23A2 209237 s at fs.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_005116
NM_203327

NM_018824
NM_001355430
NM_001355431

RefSeq (protein)

NP_005107
NP_976072

NP_061294
NP_001342359
NP_001342360

Location (UCSC)Chr 20: 4.85 – 5.01 MbChr 2: 132.05 – 132.15 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Solute carrier family 23 member 2 is a protein that in humans is encoded by the SLC23A2 gene.[5][6][7]

The absorption of vitamin C into the body and its distribution to organs requires two sodium-dependent vitamin C transporters. This gene encodes one of the two required transporters and the encoded protein accounts for tissue-specific uptake of vitamin C. Previously, this gene had an official symbol of SLC23A1.[7]

See also[edit]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000089057 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000027340 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:".
  4. ^ "Mouse PubMed Reference:".
  5. ^ Faaland CA, Race JE, Ricken G, Warner FJ, Williams WJ, Holtzman EJ (Dec 1998). "Molecular characterization of two novel transporters from human and mouse kidney and from LLC-PK1 cells reveals a novel conserved family that is homologous to bacterial and Aspergillus nucleobase transporters". Biochim Biophys Acta. 1442 (2–3): 353–60. doi:10.1016/S0167-4781(98)00151-1. PMID 9804989.
  6. ^ Tsukaguchi H, Tokui T, Mackenzie B, Berger UV, Chen XZ, Wang Y, Brubaker RF, Hediger MA (Jun 1999). "A family of mammalian Na+-dependent L-ascorbic acid transporters". Nature. 399 (6731): 70–5. doi:10.1038/19986. PMID 10331392.
  7. ^ a b "Entrez Gene: SLC23A2 solute carrier family 23 (nucleobase transporters), member 2".

Further reading[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.