SLC25A11

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SLC25A11
Identifiers
AliasesSLC25A11, OGC, SLC20A4, solute carrier family 25 member 11
External IDsMGI: 1915113 HomoloGene: 2637 GeneCards: SLC25A11
Gene location (Human)
Chromosome 17 (human)
Chr.Chromosome 17 (human)[1]
Chromosome 17 (human)
Genomic location for SLC25A11
Genomic location for SLC25A11
Band17p13.2Start4,937,130 bp[1]
End4,940,251 bp[1]
RNA expression pattern
PBB GE SLC25A11 209003 at fs.png

PBB GE SLC25A11 207088 s at fs.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_003562
NM_001165417
NM_001165418

NM_024211

RefSeq (protein)

NP_001158889
NP_001158890
NP_003553

NP_077173

Location (UCSC)Chr 17: 4.94 – 4.94 MbChr 11: 70.64 – 70.65 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Mitochondrial 2-oxoglutarate/malate carrier protein is a protein that in humans is encoded by the SLC25A11 gene.[5][6][7] Inactivating mutations in this gene predispose to metastasic paraganglioma.[8]


See also[edit]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000108528 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000014606 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". 
  4. ^ "Mouse PubMed Reference:". 
  5. ^ Piccininni S, Iacobazzi V, Lauria G, Rocchi M, Palmieri F (Mar 1999). "Assignment of the oxoglutarate carrier gene (SLC20A4) to human chromosome 17p13.3". Cytogenet Cell Genet. 83 (3–4): 256–7. doi:10.1159/000015198. PMID 10072597. 
  6. ^ Iacobazzi V, Palmieri F, Runswick MJ, Walker JE (Jan 1993). "Sequences of the human and bovine genes for the mitochondrial 2-oxoglutarate carrier". DNA Seq. 3 (2): 79–88. doi:10.3109/10425179209034000. PMID 1457818. 
  7. ^ "Entrez Gene: SLC25A11 solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11". 
  8. ^ Buffet, Alexandre; Morin, Aurelie; Castro-Vega, Luis-Jaime; Habarou, Florence; Lussey-Lepoutre, Charlotte; Letouzé, Eric; Lefebvre, Hervé; Guilhem, Isabelle; Magalie, Haissaguerre (2018-02-05). "Germline mutations in the mitochondrial 2-oxoglutarate/malate carrier SLC25A11 gene confer a predisposition to metastatic paragangliomas". Cancer Research. doi:10.1158/0008-5472.CAN-17-2463. ISSN 1538-7445. PMID 29431636. 

Further reading[edit]