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Available structures
PDB Ortholog search: PDBe RCSB
Aliases SLC25A12, AGC1, ARALAR, solute carrier family 25 member 12
External IDs MGI: 1926080 HomoloGene: 48235 GeneCards: 8604
Genetically Related Diseases
Disease Name References
amyotrophic lateral sclerosis
RNA expression pattern
PBB GE SLC25A12 203339 at tn.png

PBB GE SLC25A12 203340 s at tn.png
More reference expression data
Species Human Mouse
RefSeq (mRNA)



RefSeq (protein)



Location (UCSC) Chr 2: 171.78 – 172 Mb Chr 2: 71.27 – 71.37 Mb
PubMed search [2] [3]
View/Edit Human View/Edit Mouse

Calcium-binding mitochondrial carrier protein Aralar1 is a protein that in humans is encoded by the SLC25A12 gene.[1][2][3][4]

See also[edit]


  1. ^ del Arco A; Satrustegui J (Oct 1998). "Molecular cloning of Aralar, a new member of the mitochondrial carrier superfamily that binds calcium and is present in human muscle and brain". J Biol Chem 273 (36): 23327–34. doi:10.1074/jbc.273.36.23327. PMID 9722566. 
  2. ^ Crackower MA; Sinasac DS; Lee JR; Herbrick JA; Tsui LC; Scherer SW (Apr 2000). "Assignment of the SLC25A12 gene coding for the human calcium-binding mitochondrial solute carrier protein aralar to human chromosome 2q24". Cytogenet Cell Genet 87 (3–4): 197–8. doi:10.1159/000015465. PMID 10702666. 
  3. ^ Palmieri L; Pardo B; Lasorsa FM; del Arco A; Kobayashi K; Iijima M; Runswick MJ; Walker JE; Saheki T; Satrustegui J; Palmieri F (Sep 2001). "Citrin and aralar1 are Ca2+-stimulated aspartate/glutamate transporters in mitochondria". EMBO J 20 (18): 5060–9. doi:10.1093/emboj/20.18.5060. PMC 125626. PMID 11566871. 
  4. ^ "Entrez Gene: SLC25A12 solute carrier family 25 (mitochondrial carrier, Aralar), member 12". 

Further reading[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.