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AliasesSLC35C2, BA394O2.1, C20orf5, CGI-15, OVCOV1, solute carrier family 35 member C2
External IDsMGI: 2385166 HomoloGene: 6581 GeneCards: SLC35C2
Gene location (Human)
Chromosome 20 (human)
Chr.Chromosome 20 (human)[1]
Chromosome 20 (human)
Genomic location for SLC35C2
Genomic location for SLC35C2
Band20q13.12Start46,345,980 bp[1]
End46,364,458 bp[1]
RNA expression pattern
PBB GE SLC35C2 219447 s at fs.png
More reference expression data
RefSeq (mRNA)
RefSeq (protein)
Location (UCSC)Chr 20: 46.35 – 46.36 MbChr 2: 165.28 – 165.29 Mb
PubMed search[3][4]
View/Edit HumanView/Edit Mouse

Solute carrier family 35 member C2 is a protein that in humans is encoded by the SLC35C2 gene.[5][6][7]

Oxygenation levels play an important role in the regulation of cellular invasiveness which occurs during early implantation when the trophoblast cells invade the uterus as well as during tumour progression and metastasis. This gene, which is regulated by oxygen tension, is induced in hypoxic trophoblast cells and is overexpressed in ovarian cancer. Two protein isoforms are encoded by transcript variants of this gene.[7]


  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000080189 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000017664 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:".
  4. ^ "Mouse PubMed Reference:".
  5. ^ Lai CH, Chou CY, Ch'ang LY, Liu CS, Lin W (Aug 2000). "Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics". Genome Res. 10 (5): 703–13. doi:10.1101/gr.10.5.703. PMC 310876. PMID 10810093.
  6. ^ Fossey SC, Mychaleckyj JC, Pendleton JK, Snyder JR, Bensen JT, Hirakawa S, Rich SS, Freedman BI, Bowden DW (Sep 2001). "A high-resolution 6.0-megabase transcript map of the type 2 diabetes susceptibility region on human chromosome 20". Genomics. 76 (1–3): 45–57. doi:10.1006/geno.2001.6584. PMID 11549316.
  7. ^ a b "Entrez Gene: SLC35C2 solute carrier family 35, member C2".

Further reading[edit]