Zinc transporter ZIP6

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SLC39A6
Identifiers
AliasesSLC39A6, LIV-1, ZIP6, solute carrier family 39 member 6
External IDsOMIM: 608731 MGI: 2147279 HomoloGene: 8199 GeneCards: SLC39A6
Gene location (Human)
Chromosome 18 (human)
Chr.Chromosome 18 (human)[1]
Chromosome 18 (human)
Genomic location for SLC39A6
Genomic location for SLC39A6
Band18q12.2Start36,108,531 bp[1]
End36,129,385 bp[1]
RNA expression pattern
PBB GE SLC39A6 202089 s at fs.png

PBB GE SLC39A6 202088 at fs.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001099406
NM_012319

NM_139143

RefSeq (protein)

NP_001092876
NP_036451

NP_631882

Location (UCSC)Chr 18: 36.11 – 36.13 MbChr 18: 24.58 – 24.6 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Zinc transporter ZIP6 is a protein that in humans is encoded by the SLC39A6 gene.[5][6][7]

Zinc is an essential cofactor for hundreds of enzymes. It is involved in protein, nucleic acid, carbohydrate, and lipid metabolism, as well as in the control of gene transcription, growth, development, and differentiation. SLC39A6 belongs to a subfamily of proteins that show structural characteristics of zinc transporters (Taylor and Nicholson, 2003).[supplied by OMIM][7]

See also[edit]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000141424 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000024270 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Taylor KM, Nicholson RI (Mar 2003). "The LZT proteins; the LIV-1 subfamily of zinc transporters". Biochim Biophys Acta. 1611 (1–2): 16–30. doi:10.1016/S0005-2736(03)00048-8. PMID 12659941.
  6. ^ Taylor KM, Morgan HE, Johnson A, Hadley LJ, Nicholson RI (Sep 2003). "Structure-function analysis of LIV-1, the breast cancer-associated protein that belongs to a new subfamily of zinc transporters". Biochem J. 375 (Pt 1): 51–9. doi:10.1042/BJ20030478. PMC 1223660. PMID 12839489.
  7. ^ a b "Entrez Gene: SLC39A6 solute carrier family 39 (zinc transporter), member 6".

Further reading[edit]