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SLC41A1 is a protein that in humans is encoded by the gene SLC41A1.[1] It is homologous to the prokaryotic Mg++ transfer protein MgtE .[2]

Mutations in this gene have been associated to Nephronophthisis-like phenotypes.[3]


  1. ^ Wabakken et al. "The human solute carrier SLC41A1 belongs to a novel eukaryotic subfamily with homology to prokaryotic MgtE Mg2+ transporters" Biochemical and Biophysical Research Communications Volume 306, Issue 3, 4 July 2003, Pages 718–724 ScienceDirect link
  2. ^ Goytain, A. & Quamme, G. A. "Functional characterization of human SLC41A1, a Mg2+ transporter with similarity to prokaryotic MgtE Mg2+ transporters." Physiological Genomics 21, 337-342 (2005) open access pdf.
  3. ^ Hurd et al."Mutation of the Mg2+ transporter SLC41A1 results in a nephronophthisis-like phenotype." J Am Soc Nephrol. 2013 May;24(6):967-77. doi: 10.1681/ASN.2012101034. Epub 2013 May 9. (PMID 23661805)