Sodium bicarbonate cotransporter 3

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  (Redirected from SLC4A7)
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AliasesSLC4A7, NBC2, NBC3, NBCN1, SBC2, SLC4A6, solute carrier family 4 member 7
External IDsMGI: 2443878 HomoloGene: 2680 GeneCards: SLC4A7
Gene location (Human)
Chromosome 3 (human)
Chr.Chromosome 3 (human)[1]
Chromosome 3 (human)
Genomic location for SLC4A7
Genomic location for SLC4A7
Band3p24.1Start27,372,721 bp[1]
End27,484,420 bp[1]
RNA expression pattern
PBB GE SLC4A7 209884 s at fs.png

PBB GE SLC4A7 207604 s at fs.png

PBB GE SLC4A7 210286 s at fs.png
More reference expression data
RefSeq (mRNA)


RefSeq (protein)


Location (UCSC)Chr 3: 27.37 – 27.48 MbChr 14: 14.7 – 14.8 Mb
PubMed search[3][4]
View/Edit HumanView/Edit Mouse

Sodium bicarbonate cotransporter 3 is a protein which in humans is encoded by the SLC4A7 gene.[5]

See also[edit]


  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000033867 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000021733 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:".
  4. ^ "Mouse PubMed Reference:".
  5. ^ "Entrez Gene: SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7".

Further reading[edit]

  • Ishibashi K, Sasaki S, Marumo F (1998). "Molecular cloning of a new sodium bicarbonate cotransporter cDNA from human retina". Biochem. Biophys. Res. Commun. 246 (2): 535–8. doi:10.1006/bbrc.1998.8658. PMID 9610397.
  • Pushkin A, Abuladze N, Lee I, et al. (1999). "Mapping of the human NBC3 (SLC4A7) gene to chromosome 3p22". Genomics. 57 (2): 321–2. doi:10.1006/geno.1999.5781. PMID 10198178.
  • Pushkin A, Abuladze N, Lee I, et al. (1999). "Cloning, tissue distribution, genomic organization, and functional characterization of NBC3, a new member of the sodium bicarbonate cotransporter family". J. Biol. Chem. 274 (23): 16569–75. doi:10.1074/jbc.274.23.16569. PMID 10347222.
  • Pushkin A, Yip KP, Clark I, et al. (2000). "NBC3 expression in rabbit collecting duct: colocalization with vacuolar H+-ATPase". Am. J. Physiol. 277 (6 Pt 2): F974–81. doi:10.1152/ajprenal.1999.277.6.F974. PMID 10600945.
  • Park M, Ko SB, Choi JY, et al. (2003). "The cystic fibrosis transmembrane conductance regulator interacts with and regulates the activity of the HCO3- salvage transporter human Na+-HCO3- cotransport isoform 3". J. Biol. Chem. 277 (52): 50503–9. doi:10.1074/jbc.M201862200. PMID 12403779.
  • Loiselle FB, Jaschke P, Casey JR (2004). "Structural and functional characterization of the human NBC3 sodium/bicarbonate co-transporter carboxyl-terminal cytoplasmic domain". Mol. Membr. Biol. 20 (4): 307–17. doi:10.1080/0968768031000122520. PMID 14578046.
  • Loiselle FB, Morgan PE, Alvarez BV, Casey JR (2004). "Regulation of the human NBC3 Na+/HCO3- cotransporter by carbonic anhydrase II and PKA". Am. J. Physiol., Cell Physiol. 286 (6): C1423–33. doi:10.1152/ajpcell.00382.2003. PMID 14736710.
  • Brill LM, Salomon AR, Ficarro SB, et al. (2004). "Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry". Anal. Chem. 76 (10): 2763–72. doi:10.1021/ac035352d. PMID 15144186.
  • Jin J, Smith FD, Stark C, et al. (2004). "Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization". Curr. Biol. 14 (16): 1436–50. doi:10.1016/j.cub.2004.07.051. PMID 15324660.
  • Reiners J, van Wijk E, Märker T, et al. (2006). "Scaffold protein harmonin (USH1C) provides molecular links between Usher syndrome type 1 and type 2". Hum. Mol. Genet. 14 (24): 3933–43. doi:10.1093/hmg/ddi417. PMID 16301216.
  • Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein–protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.