SLCO1A2

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SLCO1A2
Identifiers
Aliases SLCO1A2, OATP, OATP-A, OATP1A2, SLC21A3, solute carrier organic anion transporter family member 1A2
External IDs MGI: 1351865 HomoloGene: 56603 GeneCards: SLCO1A2
Gene location (Human)
Chromosome 12 (human)
Chr. Chromosome 12 (human)[1]
Chromosome 12 (human)
Genomic location for SLCO1A2
Genomic location for SLCO1A2
Band 12p12.1 Start 21,264,600 bp[1]
End 21,419,594 bp[1]
RNA expression pattern
PBB GE SLCO1A2 211481 at fs.png

PBB GE SLCO1A2 211480 s at fs.png

PBB GE SLCO1A2 207308 at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_005075
NM_021094
NM_134431

NM_001267707
NM_130861

RefSeq (protein)

NP_066580
NP_602307

NP_001254636
NP_570931

Location (UCSC) Chr 12: 21.26 – 21.42 Mb Chr 12: 142.23 – 142.32 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Solute carrier organic anion transporter family member 1A2 is a protein that in humans is encoded by the SLCO1A2 gene.[5][6]

This gene encodes a sodium-independent transporter which mediates cellular uptake of organic ions in the liver. Its substrates include bile acids, bromosulphophthalein, and some steroidal compounds. The protein is a member of the SLC21A family of solute carriers. Alternate splicing of this gene results in three transcript variants encoding two different isoforms.[6]

See also[edit]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000084453 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000063975 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". 
  4. ^ "Mouse PubMed Reference:". 
  5. ^ Kullak-Ublick GA, Beuers U, Meier PJ, Domdey H, Paumgartner G (Apr 1997). "Assignment of the human organic anion transporting polypeptide (OATP) gene to chromosome 12p12 by fluorescence in situ hybridization". J Hepatol. 25 (6): 985–7. doi:10.1016/S0168-8278(96)80307-2. PMID 9007731. 
  6. ^ a b "Entrez Gene: SLCO1A2 solute carrier organic anion transporter family, member 1A2". 

Further reading[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.