SLIT2

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SLIT2
Protein SLIT2 PDB 2V70.png
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesSLIT2, SLIL3, Slit-2, slit guidance ligand 2
External IDsOMIM: 603746 MGI: 1315205 HomoloGene: 3516 GeneCards: SLIT2
Gene location (Human)
Chromosome 4 (human)
Chr.Chromosome 4 (human)[1]
Chromosome 4 (human)
Genomic location for SLIT2
Genomic location for SLIT2
Band4p15.31Start20,251,905 bp[1]
End20,620,561 bp[1]
RNA expression pattern
PBB GE SLIT2 209897 s at fs.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001289135
NM_001289136
NM_004787

NM_001291227
NM_001291228
NM_178804

RefSeq (protein)

NP_001276064
NP_001276065
NP_004778

NP_001278156
NP_001278157
NP_848919

Location (UCSC)Chr 4: 20.25 – 20.62 MbChr 5: 47.98 – 48.31 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Slit homolog 2 protein is a protein that in humans is encoded by the SLIT2 gene.[5][6][7]

Interactions[edit]

SLIT2 has been shown to interact with Glypican 1.[8]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000145147 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000031558 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Itoh A; Miyabayashi T; Ohno M; Sakano S (February 1999). "Cloning and expressions of three mammalian homologues of Drosophila slit suggest possible roles for Slit in the formation and maintenance of the nervous system". Brain Res Mol Brain Res. 62 (2): 175–86. doi:10.1016/S0169-328X(98)00224-1. PMID 9813312.
  6. ^ Chedotal A (February 2008). "Slits and their receptors". Adv Exp Med Biol. 621: 65–80. doi:10.1007/978-0-387-76715-4_5. PMID 18269211.
  7. ^ "Entrez Gene: SLIT2 slit homolog 2 (Drosophila)".
  8. ^ Ronca, F; Andersen J S; Paech V; Margolis R U (August 2001). "Characterization of Slit protein interactions with glypican-1". J. Biol. Chem. United States. 276 (31): 29141–7. doi:10.1074/jbc.M100240200. ISSN 0021-9258. PMID 11375980.

Further reading[edit]