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Structural maintenance of chromosomes 1B
Symbols SMC1B ; SMC1BETA; SMC1L2
External IDs OMIM608685 MGI2154049 HomoloGene13786 GeneCards: SMC1B Gene
Species Human Mouse
Entrez 27127 140557
Ensembl ENSG00000077935 ENSMUSG00000022432
UniProt Q8NDV3 Q920F6
RefSeq (mRNA) NM_001291501 NM_080470
RefSeq (protein) NP_001278430 NP_536718
Location (UCSC) Chr 22:
45.34 – 45.41 Mb
Chr 15:
85.06 – 85.13 Mb
PubMed search [1] [2]

Structural maintenance of chromosomes protein 1B (SMC-1B) is a protein that in humans is encoded by the SMC1B gene.[1][2][3] SMC-1B belongs to a family of proteins required for chromatid cohesion and DNA recombination during meiosis and mitosis.[3]


  1. ^ "Entrez Gene: structural maintenance of chromosomes 1B". 
  2. ^ Dunham I, Shimizu N, Roe BA, Chissoe S, Hunt AR, Collins JE, Bruskiewich R, Beare DM, Clamp M, Smink LJ, Ainscough R, Almeida JP, Babbage A, Bagguley C, Bailey J, Barlow K, Bates KN, Beasley O, Bird CP, Blakey S, Bridgeman AM, Buck D, Burgess J, Burrill WD, O'Brien KP (December 1999). "The DNA sequence of human chromosome 22". Nature 402 (6761): 489–95. doi:10.1038/990031. PMID 10591208. 
  3. ^ a b Revenkova E, Eijpe M, Heyting C, Gross B, Jessberger R (October 2001). "Novel meiosis-specific isoform of mammalian SMC1". Mol. Cell. Biol. 21 (20): 6984–98. doi:10.1128/MCB.21.20.6984-6998.2001. PMC 99874. PMID 11564881. 

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