SMC5

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SMC5
Identifiers
Aliases SMC5, SMC5L1, structural maintenance of chromosomes 5
External IDs MGI: 2385088 HomoloGene: 41009 GeneCards: SMC5
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_015110

NM_001252684
NM_001252685
NM_153808

RefSeq (protein)

NP_055925.2

NP_001239613.1
NP_722503.1

Location (UCSC) Chr 9: 70.26 – 70.35 Mb Chr 19: 23.21 – 23.27 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Structural maintenance of chromosomes protein 5 is a protein encoded by the SMC5 gene in human.[3][4]

It is involved in the Alternative lengthening of telomeres cancer mechanism.[5]


References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Nagase T, Ishikawa K, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (Aug 1998). "Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro". DNA Res. 5 (1): 31–9. doi:10.1093/dnares/5.1.31. PMID 9628581. 
  4. ^ "Entrez Gene: SMC5 structural maintenance of chromosomes 5". 
  5. ^ Potts PR, Yu H (2007). "The SMC5/6 complex maintains telomere length in ALT cancer cells through SUMOylation of telomere-binding proteins". Nat. Struct. Mol. Biol. 14 (7): 581–90. doi:10.1038/nsmb1259. PMID 17589526. 

Further reading[edit]