SMCR7L

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MIEF1
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases MIEF1, HSU79252, MID51, SMCR7L, dJ1104E15.3, mitochondrial elongation factor 1
External IDs MGI: 2146020 HomoloGene: 10374 GeneCards: MIEF1
RNA expression pattern
PBB GE SMCR7L 221516 s at fs.png

PBB GE SMCR7L 204594 s at fs.png

PBB GE SMCR7L 204593 s at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001304564
NM_013298
NM_019008

NM_178719

RefSeq (protein)

NP_001291493
NP_061881

NP_848834.2
NP_848834

Location (UCSC) Chr 22: 39.5 – 39.52 Mb Chr 15: 80.23 – 80.25 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Mitochondrial dynamic protein MID51 (MID51) also known as mitochondrial elongation factor 1 (MIEF1) or Smith-Magenis syndrome chromosome region candidate gene 7 protein-like (SMCR7L) is a protein that in humans is encoded by the SMCR7L gene.[3][4][5]

Function[edit]

The SMCR7L gene codes for a protein that has been called MiD51/MIEF1 and shown to regulate mitochondrial fission by interacting with the proteins Drp1 and FIS1.[6]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Wiemann S; Weil B; Wellenreuther R; Gassenhuber J; Glassl S; Ansorge W; Bocher M; Blocker H; Bauersachs S; Blum H; Lauber J; Dusterhoft A; Beyer A; Kohrer K; Strack N; Mewes HW; Ottenwalder B; Obermaier B; Tampe J; Heubner D; Wambutt R; Korn B; Klein M; Poustka A (Mar 2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072Freely accessible. PMID 11230166. 
  4. ^ Andersson B; Wentland MA; Ricafrente JY; Liu W; Gibbs RA (Jun 1996). "A "double adaptor" method for improved shotgun library construction". Anal Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474. 
  5. ^ "Entrez Gene: SMCR7L Smith-Magenis syndrome chromosome region, candidate 7-like". 
  6. ^ Dikov, D.; Reichert, A. S. (2011). "How to split up: Lessons from mitochondria". The EMBO Journal. 30 (14): 2751–2753. doi:10.1038/emboj.2011.219. PMC 3160261Freely accessible. PMID 21772324. 

Further reading[edit]