SNF1LK2

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SIK2
Identifiers
Aliases SIK2, LOH11CR1I, QIK, SNF1LK2, SIK-2, salt inducible kinase 2
External IDs MGI: 2445031 HomoloGene: 22875 GeneCards: 23235
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_015191

NM_178710

RefSeq (protein)

NP_056006.1

NP_848825.2

Location (UCSC) Chr 11: 111.6 – 111.73 Mb Chr 9: 50.89 – 51.01 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Serine/threonine-protein kinase SIK2 is an enzyme that in humans is encoded by the SIK2 gene.[3][4]

Interactions[edit]

SNF1LK2 has been shown to interact with CRTC2.[5]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Katoh M, Katoh M (May 2004). "Identification and characterization of human FOXN5 and rat Foxn5 genes in silico". International Journal of Oncology. 24 (5): 1339–44. doi:10.3892/ijo.24.5.1339. PMID 15067358. 
  4. ^ "Entrez Gene: SNF1LK2 SNF1-like kinase 2". 
  5. ^ Screaton RA, Conkright MD, Katoh Y, Best JL, Canettieri G, Jeffries S, Guzman E, Niessen S, Yates JR, Takemori H, Okamoto M, Montminy M (Oct 2004). "The CREB coactivator TORC2 functions as a calcium- and cAMP-sensitive coincidence detector". Cell. 119 (1): 61–74. doi:10.1016/j.cell.2004.09.015. PMID 15454081. 

Further reading[edit]

  • Nakajima D, Okazaki N, Yamakawa H, Kikuno R, Ohara O, Nagase T (Jun 2002). "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones". DNA Research. 9 (3): 99–106. doi:10.1093/dnares/9.3.99. PMID 12168954. 
  • Bonaldo MF, Lennon G, Soares MB (Sep 1996). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Research. 6 (9): 791–806. doi:10.1101/gr.6.9.791. PMID 8889548. 
  • Nagase T, Ishikawa K, Suyama M, Kikuno R, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (Oct 1998). "Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Research. 5 (5): 277–86. doi:10.1093/dnares/5.5.277. PMID 9872452. 
  • Wiemann S, Weil B, Wellenreuther R, Gassenhuber J, Glassl S, Ansorge W, Böcher M, Blöcker H, Bauersachs S, Blum H, Lauber J, Düsterhöft A, Beyer A, Köhrer K, Strack N, Mewes HW, Ottenwälder B, Obermaier B, Tampe J, Heubner D, Wambutt R, Korn B, Klein M, Poustka A (Mar 2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Research. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072free to read. PMID 11230166. 
  • Horike N, Takemori H, Katoh Y, Doi J, Min L, Asano T, Sun XJ, Yamamoto H, Kasayama S, Muraoka M, Nonaka Y, Okamoto M (May 2003). "Adipose-specific expression, phosphorylation of Ser794 in insulin receptor substrate-1, and activation in diabetic animals of salt-inducible kinase-2". The Journal of Biological Chemistry. 278 (20): 18440–7. doi:10.1074/jbc.M211770200. PMID 12624099. 
  • Katoh M, Katoh M (Nov 2003). "Identification and characterization of human KIAA1391 and mouse Kiaa1391 genes encoding novel RhoGAP family proteins with RA domain and ANXL repeats". International Journal of Oncology. 23 (5): 1471–6. doi:10.3892/ijo.23.5.1471. PMID 14532992. 
  • Lizcano JM, Göransson O, Toth R, Deak M, Morrice NA, Boudeau J, Hawley SA, Udd L, Mäkelä TP, Hardie DG, Alessi DR (Feb 2004). "LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR-1". The EMBO Journal. 23 (4): 833–43. doi:10.1038/sj.emboj.7600110. PMC 381014free to read. PMID 14976552. 
  • Screaton RA, Conkright MD, Katoh Y, Best JL, Canettieri G, Jeffries S, Guzman E, Niessen S, Yates JR, Takemori H, Okamoto M, Montminy M (Oct 2004). "The CREB coactivator TORC2 functions as a calcium- and cAMP-sensitive coincidence detector". Cell. 119 (1): 61–74. doi:10.1016/j.cell.2004.09.015. PMID 15454081. 
  • Katoh Y, Takemori H, Min L, Muraoka M, Doi J, Horike N, Okamoto M (Nov 2004). "Salt-inducible kinase-1 represses cAMP response element-binding protein activity both in the nucleus and in the cytoplasm". European Journal of Biochemistry / FEBS. 271 (21): 4307–19. doi:10.1111/j.1432-1033.2004.04372.x. PMID 15511237.