SNRPD3

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SNRPD3
Protein SNRPD3 PDB 1d3b.png
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases SNRPD3, SMD3, Sm-D3, small nuclear ribonucleoprotein D3 polypeptide
External IDs MGI: 1914582 HomoloGene: 3078 GeneCards: SNRPD3
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001278656
NM_004175

NM_026095

RefSeq (protein)

NP_001265585
NP_004166

NP_080371.1
NP_080371

Location (UCSC) Chr 22: 24.56 – 24.61 Mb Chr 10: 75.52 – 75.54 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Small nuclear ribonucleoprotein Sm D3 is a protein that in humans is encoded by the SNRPD3 gene.[3][4][5]

Function[edit]

The protein encoded by this gene belongs to the small nuclear ribonucleoprotein core protein family. It is required for pre-mRNA splicing and small nuclear ribonucleoprotein biogenesis.[5]

Interactions[edit]

SNRPD3 has been shown to interact with:

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Lehmeier T, Foulaki K, Lührmann R (January 1991). "Evidence for three distinct D proteins, which react differentially with anti-Sm autoantibodies, in the cores of the major snRNPs U1, U2, U4/U6 and U5". Nucleic Acids Res. 18 (22): 6475–84. doi:10.1093/nar/18.22.6475. PMC 332598Freely accessible. PMID 1701240. 
  4. ^ Lehmeier T, Raker V, Hermann H, Lührmann R (January 1995). "cDNA cloning of the Sm proteins D2 and D3 from human small nuclear ribonucleoproteins: evidence for a direct D1-D2 interaction". Proc Natl Acad Sci U S A. 91 (25): 12317–21. doi:10.1073/pnas.91.25.12317. PMC 45428Freely accessible. PMID 7527560. 
  5. ^ a b "Entrez Gene: SNRPD3 small nuclear ribonucleoprotein D3 polypeptide 18kDa". 
  6. ^ Ajuh P, Kuster B, Panov K, Zomerdijk JC, Mann M, Lamond AI (Dec 2000). "Functional analysis of the human CDC5L complex and identification of its components by mass spectrometry". EMBO J. 19 (23): 6569–81. doi:10.1093/emboj/19.23.6569. PMC 305846Freely accessible. PMID 11101529. 
  7. ^ a b Friesen WJ, Paushkin S, Wyce A, Massenet S, Pesiridis GS, Van Duyne G, Rappsilber J, Mann M, Dreyfuss G (Dec 2001). "The methylosome, a 20S complex containing JBP1 and pICln, produces dimethylarginine-modified Sm proteins". Mol. Cell. Biol. 21 (24): 8289–300. doi:10.1128/MCB.21.24.8289-8300.2001. PMC 99994Freely accessible. PMID 11713266. 
  8. ^ Charroux B, Pellizzoni L, Perkinson RA, Shevchenko A, Mann M, Dreyfuss G (Dec 1999). "Gemin3: A novel DEAD box protein that interacts with SMN, the spinal muscular atrophy gene product, and is a component of gems". J. Cell Biol. 147 (6): 1181–94. doi:10.1083/jcb.147.6.1181. PMC 2168095Freely accessible. PMID 10601333. 

Further reading[edit]