SNX21

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SNX21
Identifiers
Aliases SNX21, C20orf161, PP3993, SNX-L, dJ337O18.4, sorting nexin family member 21
External IDs MGI: 1917729 HomoloGene: 43132 GeneCards: SNX21
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001042632
NM_001042633
NM_033421
NM_152897

NM_133924

RefSeq (protein)

NP_001036097
NP_001036098
NP_219489
NP_690857

NP_598685.2
NP_598685

Location (UCSC) Chr 20: 45.83 – 45.84 Mb Chr 2: 164.79 – 164.79 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Sorting nexin-21 is a protein that in humans is encoded by the SNX21 gene.[3][4][5]

This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region, like some family members. The specific function of this protein has not been determined. Multiple transcript variants encoding distinct isoforms have been identified for this gene.[5]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Worby CA, Dixon JE (Dec 2002). "Sorting out the cellular functions of sorting nexins". Nat Rev Mol Cell Biol. 3 (12): 919–31. doi:10.1038/nrm974. PMID 12461558. 
  4. ^ Zeng W, Yuan W, Wang Y, Jiao W, Zhu Y, Huang C, Li D, Li Y, Zhu C, Wu X, Liu M (Dec 2002). "Expression of a novel member of sorting nexin gene family, SNX-L, in human liver development". Biochem Biophys Res Commun. 299 (4): 542–8. doi:10.1016/S0006-291X(02)02695-5. PMID 12459172. 
  5. ^ a b "Entrez Gene: SNX21 sorting nexin family member 21". 

Further reading[edit]