SNX27

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SNX27
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesSNX27, MRT1, MY014, sorting nexin family member 27
External IDsMGI: 1923992 HomoloGene: 12797 GeneCards: SNX27
Gene location (Human)
Chromosome 1 (human)
Chr.Chromosome 1 (human)[1]
Chromosome 1 (human)
Genomic location for SNX27
Genomic location for SNX27
Band1q21.3Start151,612,006 bp[1]
End151,699,091 bp[1]
RNA expression pattern
PBB GE SNX27 221006 s at fs.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_030918
NM_001330723

NM_001082484
NM_029721

RefSeq (protein)

NP_001317652
NP_112180

NP_001075953
NP_083997

Location (UCSC)Chr 1: 151.61 – 151.7 MbChr 3: 94.5 – 94.58 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Sorting nexin family member 27, also known as SNX27, is a human gene.[5]

This gene encodes a member of the sorting nexin family, a diverse group of cytoplasmic and membrane-associated proteins involved in endocytosis of plasma membrane receptors and protein trafficking through these compartments. All members of this protein family contain a phosphoinositide binding domain (PX domain). A highly similar protein in mice is responsible for the specific recruitment of an isoform of the serotonin 5-hydroxytryptamine 4 receptor into early endosomes, suggesting the analogous role for the human protein.[5]

References[edit]

Further reading[edit]