Sp4 transcription factor

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Sp4 transcription factor
Protein SP4 PDB 1va1.png
PDB rendering based on 1va1.
Available structures
PDB Ortholog search: PDBe, RCSB
Symbols SP4 ; HF1B; SPR-1
External IDs OMIM600540 MGI107595 HomoloGene2341 GeneCards: SP4 Gene
RNA expression pattern
PBB GE SP4 206663 at tn.png
More reference expression data
Species Human Mouse
Entrez 6671 20688
Ensembl ENSG00000105866 ENSMUSG00000025323
UniProt Q02446 Q62445
RefSeq (mRNA) NM_003112 NM_001166385
RefSeq (protein) NP_003103 NP_001159857
Location (UCSC) Chr 7:
21.43 – 21.51 Mb
Chr 12:
118.23 – 118.3 Mb
PubMed search [1] [2]

Transcription factor Sp4 is a protein that in humans is encoded by the SP4 gene.[1][2]


Sp4 transcription factor has been shown to interact with E2F1.[3]


  1. ^ Hagen G, Müller S, Beato M, Suske G (Nov 1992). "Cloning by recognition site screening of two novel GT box binding proteins: a family of Sp1 related genes". Nucleic Acids Research 20 (21): 5519–25. doi:10.1093/nar/20.21.5519. PMC 334381. PMID 1454515. 
  2. ^ "Entrez Gene: SP4 Sp4 transcription factor". 
  3. ^ Rotheneder H, Geymayer S, Haidweger E (Nov 1999). "Transcription factors of the Sp1 family: interaction with E2F and regulation of the murine thymidine kinase promoter". Journal of Molecular Biology 293 (5): 1005–15. doi:10.1006/jmbi.1999.3213. PMID 10547281. 

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