SSPO

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SSPO
Identifiers
Aliases SSPO
External IDs MGI: 2674311 HomoloGene: 45453 GeneCards: 23145
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_198455

NM_173428

RefSeq (protein)

NP_940857.2

n/a

Location (UCSC) Chr 7: 149.78 – 149.83 Mb Chr 6: 48.45 – 48.5 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

SCO-spondin is a protein that in humans is encoded by the SSPO gene.[1][2][3] SCO-spondin is secreted by the subcommissural organ, and contributes to commissural axon growth and the formation of Reissner's fiber, a fibrous aggregation of secreted molecules extending from the subcommissural organ to the end of the spinal cord.[4]

References[edit]

  1. ^ Gobron S, Monnerie H, Meiniel R, Creveaux I, Lehmann W, Lamalle D, Dastugue B, Meiniel A (May 1996). "SCO-spondin: a new member of the thrombospondin family secreted by the subcommissural organ is a candidate in the modulation of neuronal aggregation". Journal of Cell Science. 109. 109 ( Pt 5): 1053–61. PMID 8743952. 
  2. ^ Gobron S, Creveaux I, Meiniel R, Didier R, Herbet A, Bamdad M, El Bitar F, Dastugue B, Meiniel A (November 2000). "Subcommissural organ/Reissner's fiber complex: characterization of SCO-spondin, a glycoprotein with potent activity on neurite outgrowth". Glia 32 (2): 177–91. doi:10.1002/1098-1136(200011)32:2<177::AID-GLIA70>3.0.CO;2-V. PMID 11008217. 
  3. ^ "Entrez Gene: SSPO SCO-spondin homolog (Bos taurus)". 
  4. ^ Gobron S, Creveaux I, Meiniel R, Didier R, Dastugue B, Meiniel A (January 1999). "SCO-spondin is evolutionarily conserved in the central nervous system of the chordate phylum". Neuroscience 88 (2): 655–64. doi:10.1016/s0306-4522(98)00252-8. PMID 10197783. 

Further reading[edit]