STRN4

STRN4
Identifiers
Aliases	STRN4, ZIN, zinedin, PPP2R6C, striatin 4
External IDs	OMIM: 614767; MGI: 2142346; HomoloGene: 8378; GeneCards: STRN4; OMA:STRN4 - orthologs
Gene location (Human)
Chr.	Chromosome 19 (human)
End	46,746,994 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	16,574,856 bp
RNA expression pattern
	Top expressed in
	left testis; ; right testis; ; sural nerve; ; ganglionic eminence; ; stromal cell of endometrium; ; ventricular zone; ; body of uterus; ; granulocyte; ; muscle layer of sigmoid colon; ; apex of heart;
	Top expressed in
	spermatocyte; ; dentate gyrus of hippocampal formation granule cell; ; spermatid; ; superior frontal gyrus; ; primary visual cortex; ; neural layer of retina; ; ventricular zone; ; internal carotid artery; ; hippocampus proper; ; external carotid artery;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein phosphatase 2A binding; protein binding; calmodulin binding; armadillo repeat domain binding; protein domain specific binding; protein-containing complex binding;
Cellular component	cytoplasm; dendritic spine; protein phosphatase type 2A complex; cell projection; membrane; protein-containing complex; dendrite; FAR/SIN/STRIPAK complex;
Biological process	biological process;
	Sources:Amigo / QuickGO
Orthologs
	29888
	97387
	ENSG00000090372
	ENSMUSG00000030374
	Q9NRL3
	P58404
	NM_001039877; NM_013403
	NM_001039878; NM_133789
	NP_001034966; NP_037535
	NP_001034967; NP_598550
	Wikidata
View/Edit Human	View/Edit Mouse

Striatin-4 is a protein that in humans is encoded by the STRN4 gene.^[5]^[6]

Interactions

STRN4 has been shown to interact with STK24.^[7]^[8]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000090372 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000030374 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Castets F, Rakitina T, Gaillard S, Moqrich A, Mattei MG, Monneron A (Aug 2000). "Zinedin, SG2NA, and striatin are calmodulin-binding, WD repeat proteins principally expressed in the brain". J. Biol. Chem. 275 (26): 19970–7. doi:10.1074/jbc.M909782199. PMID 10748158.{{cite journal}}: CS1 maint: unflagged free DOI (link)
^ "Entrez Gene: STRN4 striatin, calmodulin binding protein 4".
^ Ewing RM, Chu P, Elisma F, Li H, Taylor P, Climie S, McBroom-Cerajewski L, Robinson MD, O'Connor L, Li M, Taylor R, Dharsee M, Ho Y, Heilbut A, Moore L, Zhang S, Ornatsky O, Bukhman YV, Ethier M, Sheng Y, Vasilescu J, Abu-Farha M, Lambert JP, Duewel HS, Stewart II, Kuehl B, Hogue K, Colwill K, Gladwish K, Muskat B, Kinach R, Adams SL, Moran MF, Morin GB, Topaloglou T, Figeys D (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.
^ Goudreault M, D'Ambrosio LM, Kean MJ, Mullin MJ, Larsen BG, Sanchez A, Chaudhry S, Chen GI, Sicheri F, Nesvizhskii AI, Aebersold R, Raught B, Gingras AC (Jan 2009). "A PP2A phosphatase high density interaction network identifies a novel striatin-interacting phosphatase and kinase complex linked to the cerebral cavernous malformation 3 (CCM3) protein". Mol. Cell Proteomics. 8 (1): 157–71. doi:10.1074/mcp.M800266-MCP200. PMC 2621004. PMID 18782753.{{cite journal}}: CS1 maint: unflagged free DOI (link)

Ewing RM, Chu P, Elisma F, Li H, Taylor P, Climie S, McBroom-Cerajewski L, Robinson MD, O'Connor L, Li M, Taylor R, Dharsee M, Ho Y, Heilbut A, Moore L, Zhang S, Ornatsky O, Bukhman YV, Ethier M, Sheng Y, Vasilescu J, Abu-Farha M, Lambert JP, Duewel HS, Stewart II, Kuehl B, Hogue K, Colwill K, Gladwish K, Muskat B, Kinach R, Adams SL, Moran MF, Morin GB, Topaloglou T, Figeys D (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.
Gaillard S, Bartoli M, Castets F, Monneron A (2001). "Striatin, a calmodulin-dependent scaffolding protein, directly binds caveolin-1". FEBS Lett. 508 (1): 49–52. doi:10.1016/S0014-5793(01)03020-4. PMID 11707266.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano S (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.

This article on a gene on human chromosome 19 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000090372 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000030374 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid10748158-5] Castets F, Rakitina T, Gaillard S, Moqrich A, Mattei MG, Monneron A (Aug 2000). "Zinedin, SG2NA, and striatin are calmodulin-binding, WD repeat proteins principally expressed in the brain". J. Biol. Chem. 275 (26): 19970–7. doi:10.1074/jbc.M909782199. PMID 10748158.{{cite journal}}: CS1 maint: unflagged free DOI (link)

[entrez-6] "Entrez Gene: STRN4 striatin, calmodulin binding protein 4".

[pmid17353931-7] Ewing RM, Chu P, Elisma F, Li H, Taylor P, Climie S, McBroom-Cerajewski L, Robinson MD, O'Connor L, Li M, Taylor R, Dharsee M, Ho Y, Heilbut A, Moore L, Zhang S, Ornatsky O, Bukhman YV, Ethier M, Sheng Y, Vasilescu J, Abu-Farha M, Lambert JP, Duewel HS, Stewart II, Kuehl B, Hogue K, Colwill K, Gladwish K, Muskat B, Kinach R, Adams SL, Moran MF, Morin GB, Topaloglou T, Figeys D (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.

[pmid18782753-8] Goudreault M, D'Ambrosio LM, Kean MJ, Mullin MJ, Larsen BG, Sanchez A, Chaudhry S, Chen GI, Sicheri F, Nesvizhskii AI, Aebersold R, Raught B, Gingras AC (Jan 2009). "A PP2A phosphatase high density interaction network identifies a novel striatin-interacting phosphatase and kinase complex linked to the cerebral cavernous malformation 3 (CCM3) protein". Mol. Cell Proteomics. 8 (1): 157–71. doi:10.1074/mcp.M800266-MCP200. PMC 2621004. PMID 18782753.{{cite journal}}: CS1 maint: unflagged free DOI (link)

[1]

[2]

[3]

[4]

[5]

[6]

[7]

[8]

Interactions

References

Further reading