STX11

From Wikipedia, the free encyclopedia
Jump to: navigation, search
STX11
Identifiers
Aliases STX11, FHL4, HLH4, HPLH4, syntaxin 11
External IDs OMIM: 605014 MGI: 1921982 HomoloGene: 2792 GeneCards: STX11
RNA expression pattern
PBB GE STX11 210190 at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_003764

NM_001163590
NM_001163591
NM_029075

RefSeq (protein)

NP_003755

NP_083351.1
NP_001157062
NP_001157063
NP_083351

Location (UCSC) Chr 6: 144.15 – 144.19 Mb Chr 10: 12.94 – 12.96 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Syntaxin 11, also known as STX11, is a human gene that is a member of the t-SNARE family.[3]

Interactions[edit]

STX11 has been shown to interact with SNAP-25[4][5] and SNAP23.[4][6]

See also[edit]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ "Entrez Gene: STX11 syntaxin 11". 
  4. ^ a b Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M (Oct 2005). "Towards a proteome-scale map of the human protein–protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514. 
  5. ^ Stelzl U, Worm U, Lalowski M, Haenig C, Brembeck FH, Goehler H, Stroedicke M, Zenkner M, Schoenherr A, Koeppen S, Timm J, Mintzlaff S, Abraham C, Bock N, Kietzmann S, Goedde A, Toksöz E, Droege A, Krobitsch S, Korn B, Birchmeier W, Lehrach H, Wanker EE (Sep 2005). "A human protein–protein interaction network: a resource for annotating the proteome". Cell. 122 (6): 957–68. doi:10.1016/j.cell.2005.08.029. PMID 16169070. 
  6. ^ Valdez AC, Cabaniols JP, Brown MJ, Roche PA (Mar 1999). "Syntaxin 11 is associated with SNAP-23 on late endosomes and the trans-Golgi network". Journal of Cell Science. 112 ( Pt 6) (6): 845–54. PMID 10036234. 

Further reading[edit]

  • Advani RJ, Bae HR, Bock JB, Chao DS, Doung YC, Prekeris R, Yoo JS, Scheller RH (Apr 1998). "Seven novel mammalian SNARE proteins localize to distinct membrane compartments". The Journal of Biological Chemistry. 273 (17): 10317–24. doi:10.1074/jbc.273.17.10317. PMID 9553086. 
  • Tang BL, Low DY, Hong W (Apr 1998). "Syntaxin 11: a member of the syntaxin family without a carboxyl terminal transmembrane domain". Biochemical and Biophysical Research Communications. 245 (2): 627–32. doi:10.1006/bbrc.1998.8490. PMID 9571206. 
  • Valdez AC, Cabaniols JP, Brown MJ, Roche PA (Mar 1999). "Syntaxin 11 is associated with SNAP-23 on late endosomes and the trans-Golgi network". Journal of Cell Science. 112 ( Pt 6) (6): 845–54. PMID 10036234. 
  • Martín-Martín B, Nabokina SM, Lazo PA, Mollinedo F (Mar 1999). "Co-expression of several human syntaxin genes in neutrophils and differentiating HL-60 cells: variant isoforms and detection of syntaxin 1". Journal of Leukocyte Biology. 65 (3): 397–406. PMID 10080545. 
  • Roperch JP, Lethrone F, Prieur S, Piouffre L, Israeli D, Tuynder M, Nemani M, Pasturaud P, Gendron MC, Dausset J, Oren M, Amson RB, Telerman A (Jul 1999). "SIAH-1 promotes apoptosis and tumor suppression through a network involving the regulation of protein folding, unfolding, and trafficking: identification of common effectors with p53 and p21(Waf1)". Proceedings of the National Academy of Sciences of the United States of America. 96 (14): 8070–3. doi:10.1073/pnas.96.14.8070. PMC 22189Freely accessible. PMID 10393949. 
  • zur Stadt U, Schmidt S, Kasper B, Beutel K, Diler AS, Henter JI, Kabisch H, Schneppenheim R, Nürnberg P, Janka G, Hennies HC (Mar 2005). "Linkage of familial hemophagocytic lymphohistiocytosis (FHL) type-4 to chromosome 6q24 and identification of mutations in syntaxin 11". Human Molecular Genetics. 14 (6): 827–34. doi:10.1093/hmg/ddi076. PMID 15703195. 
  • Stelzl U, Worm U, Lalowski M, Haenig C, Brembeck FH, Goehler H, Stroedicke M, Zenkner M, Schoenherr A, Koeppen S, Timm J, Mintzlaff S, Abraham C, Bock N, Kietzmann S, Goedde A, Toksöz E, Droege A, Krobitsch S, Korn B, Birchmeier W, Lehrach H, Wanker EE (Sep 2005). "A human protein–protein interaction network: a resource for annotating the proteome". Cell. 122 (6): 957–68. doi:10.1016/j.cell.2005.08.029. PMID 16169070. 
  • Yamamoto K, Ishii E, Horiuchi H, Ueda I, Ohga S, Nishi M, Ogata Y, Zaitsu M, Morimoto A, Hara T, Imashuku S, Sasazuki T, Yasukawa M (2006). "Mutations of syntaxin 11 and SNAP23 genes as causes of familial hemophagocytic lymphohistiocytosis were not found in Japanese people". Journal of Human Genetics. 50 (11): 600–3. doi:10.1007/s10038-005-0293-1. PMID 16180048. 
  • Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M (Oct 2005). "Towards a proteome-scale map of the human protein–protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514. 
  • Zur Stadt U, Beutel K, Kolberg S, Schneppenheim R, Kabisch H, Janka G, Hennies HC (Jan 2006). "Mutation spectrum in children with primary hemophagocytic lymphohistiocytosis: molecular and functional analyses of PRF1, UNC13D, STX11, and RAB27A". Human Mutation. 27 (1): 62–8. doi:10.1002/humu.20274. PMID 16278825. 
  • Bryceson YT, Rudd E, Zheng C, Edner J, Ma D, Wood SM, Bechensteen AG, Boelens JJ, Celkan T, Farah RA, Hultenby K, Winiarski J, Roche PA, Nordenskjöld M, Henter JI, Long EO, Ljunggren HG (Sep 2007). "Defective cytotoxic lymphocyte degranulation in syntaxin-11 deficient familial hemophagocytic lymphohistiocytosis 4 (FHL4) patients". Blood. 110 (6): 1906–15. doi:10.1182/blood-2007-02-074468. PMC 1976360Freely accessible. PMID 17525286. 
  • Arneson LN, Brickshawana A, Segovis CM, Schoon RA, Dick CJ, Leibson PJ (Sep 2007). "Cutting edge: syntaxin 11 regulates lymphocyte-mediated secretion and cytotoxicity". Journal of Immunology. 179 (6): 3397–401. doi:10.4049/jimmunol.179.6.3397. PMID 17785771.