STX7

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STX7
Protein STX7 PDB 1gl2.png
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases STX7
External IDs MGI: 1858210 HomoloGene: 37823 GeneCards: STX7
RNA expression pattern
PBB GE STX7 212632 at fs.png

PBB GE STX7 212631 at fs.png

PBB GE STX7 203457 at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_003569
NM_001326578
NM_001326579
NM_001326580

NM_016797

RefSeq (protein)

NP_001313507
NP_001313508
NP_001313509
NP_003560

n/a

Location (UCSC) Chr 6: 132.45 – 132.51 Mb Chr 10: 24.15 – 24.19 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Syntaxin-7 is a protein that in humans is encoded by the STX7 gene.[3][4]

In melanocytic cells STX7 gene expression may be regulated by MITF.[5]


Interactions[edit]

STX7 has been shown to interact with STX8,[6] VPS18,[7] Vesicle-associated membrane protein 8[6][8] and VPS11.[7]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Wang H, Frelin L, Pevsner J (October 1997). "Human syntaxin 7: a Pep12p/Vps6p homologue implicated in vesicle trafficking to lysosomes". Gene. 199 (1-2): 39–48. doi:10.1016/S0378-1119(97)00343-0. PMID 9358037. 
  4. ^ "Entrez Gene: STX7 syntaxin 7". 
  5. ^ Hoek KS, Schlegel NC, Eichhoff OM, Widmer DS, Praetorius C, Einarsson SO, Valgeirsdottir S, Bergsteinsdottir K, Schepsky A, Dummer R, Steingrimsson E (December 2008). "Novel MITF targets identified using a two-step DNA microarray strategy". Pigment Cell & Melanoma Research. 21 (6): 665–76. doi:10.1111/j.1755-148X.2008.00505.x. PMID 19067971. 
  6. ^ a b Antonin W, Holroyd C, Fasshauer D, Pabst S, Von Mollard GF, Jahn R (December 2000). "A SNARE complex mediating fusion of late endosomes defines conserved properties of SNARE structure and function". The EMBO Journal. 19 (23): 6453–64. doi:10.1093/emboj/19.23.6453. PMC 305878Freely accessible. PMID 11101518. 
  7. ^ a b Kim BY, Krämer H, Yamamoto A, Kominami E, Kohsaka S, Akazawa C (August 2001). "Molecular characterization of mammalian homologues of class C Vps proteins that interact with syntaxin-7". The Journal of Biological Chemistry. 276 (31): 29393–402. doi:10.1074/jbc.M101778200. PMID 11382755. 
  8. ^ Wade N, Bryant NJ, Connolly LM, Simpson RJ, Luzio JP, Piper RC, James DE (June 2001). "Syntaxin 7 complexes with mouse Vps10p tail interactor 1b, syntaxin 6, vesicle-associated membrane protein (VAMP)8, and VAMP7 in b16 melanoma cells". The Journal of Biological Chemistry. 276 (23): 19820–7. doi:10.1074/jbc.M010838200. PMID 11278762. 

Further reading[edit]