SULT1E1

From Wikipedia, the free encyclopedia
Jump to: navigation, search
SULT1E1
Protein SULT1E1 PDB 1g3m.png
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases SULT1E1, EST, EST-1, ST1E1, STE, sulfotransferase family 1E member 1
External IDs MGI: 98431 HomoloGene: 101388 GeneCards: SULT1E1
RNA expression pattern
PBB GE SULT1E1 219934 s at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_005420

NM_023135

RefSeq (protein)

NP_005411

NP_075624

Location (UCSC) Chr 4: 69.81 – 69.86 Mb Chr 5: 87.58 – 87.59 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Estrogen sulfotransferase is an enzyme that in humans is encoded by the SULT1E1 gene.[3][4]

Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. This gene encodes a protein that transfers a sulfo moiety to and from estrone, which may control levels of estrogen receptors.[4]

See also[edit]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Bernier F, Leblanc G, Labrie F, Luu-The V (Dec 1994). "Structure of human estrogen and aryl sulfotransferase gene. Two mRNA species issued from a single gene". J Biol Chem. 269 (45): 28200–5. PMID 7961757. 
  4. ^ a b "Entrez Gene: SULT1E1 sulfotransferase family 1E, estrogen-preferring, member 1". 

Further reading[edit]