SYT11

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SYT11
Identifiers
Aliases SYT11, SYT12, sytXI, synaptotagmin 11
External IDs MGI: 1859547 HomoloGene: 23120 GeneCards: SYT11
Gene location (Human)
Chromosome 1 (human)
Chr. Chromosome 1 (human)[1]
Chromosome 1 (human)
Genomic location for SYT11
Genomic location for SYT11
Band 1q22 Start 155,859,509 bp[1]
End 155,885,199 bp[1]
RNA expression pattern
PBB GE SYT11 209198 s at fs.png

PBB GE SYT11 209197 at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_152280

NM_018804

RefSeq (protein)

NP_689493

NP_061274

Location (UCSC) Chr 1: 155.86 – 155.89 Mb Chr 1: 88.74 – 88.78 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Synaptotagmin-11 is a protein that in humans is encoded by the SYT11 gene.[5][6]

Interactions[edit]

SYT11 has been shown to interact with Parkin (ligase).[7]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000132718 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000068923 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". 
  4. ^ "Mouse PubMed Reference:". 
  5. ^ Craxton M (September 2001). "Genomic analysis of synaptotagmin genes". Genomics. 77 (1–2): 43–9. doi:10.1006/geno.2001.6619. PMID 11543631. 
  6. ^ "Entrez Gene: SYT11 synaptotagmin XI". 
  7. ^ Huynh DP, Scoles DR, Nguyen D, Pulst SM (October 2003). "The autosomal recessive juvenile Parkinson disease gene product, parkin, interacts with and ubiquitinates synaptotagmin XI". Human Molecular Genetics. 12 (20): 2587–97. doi:10.1093/hmg/ddg269. PMID 12925569. 

Further reading[edit]

  • Nomura N, Nagase T, Miyajima N, Sazuka T, Tanaka A, Sato S, Seki N, Kawarabayasi Y, Ishikawa K, Tabata S (1995). "Prediction of the coding sequences of unidentified human genes. II. The coding sequences of 40 new genes (KIAA0041-KIAA0080) deduced by analysis of cDNA clones from human cell line KG-1". DNA Research. 1 (5): 223–9. doi:10.1093/dnares/1.5.223. PMID 7584044. 
  • Mizutani A, Fukuda M, Ibata K, Shiraishi Y, Mikoshiba K (March 2000). "SYNCRIP, a cytoplasmic counterpart of heterogeneous nuclear ribonucleoprotein R, interacts with ubiquitous synaptotagmin isoforms". The Journal of Biological Chemistry. 275 (13): 9823–31. doi:10.1074/jbc.275.13.9823. PMID 10734137. 
  • Huynh DP, Scoles DR, Nguyen D, Pulst SM (October 2003). "The autosomal recessive juvenile Parkinson disease gene product, parkin, interacts with and ubiquitinates synaptotagmin XI". Human Molecular Genetics. 12 (20): 2587–97. doi:10.1093/hmg/ddg269. PMID 12925569. 
  • Glass AS, Huynh DP, Franck T, Woitalla D, Müller T, Pulst SM, Berg D, Krüger R, Riess O (2004). "Screening for mutations in synaptotagmin XI in Parkinson's disease". Journal of Neural Transmission. Supplementum (68): 21–8. PMID 15354386. 
  • Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M (October 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514. 
  • Inoue S, Imamura A, Okazaki Y, Yokota H, Arai M, Hayashi N, Furukawa A, Itokawa M, Oishi M (April 2007). "Synaptotagmin XI as a candidate gene for susceptibility to schizophrenia". American Journal of Medical Genetics Part B. 144B (3): 332–40. doi:10.1002/ajmg.b.30465. PMID 17192956.