SYT13

From Wikipedia, the free encyclopedia
Jump to navigation Jump to search
SYT13
Protein SYT13 PDB 1wfm.png
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesSYT13, synaptotagmin 13
External IDsOMIM: 607716 MGI: 1933945 HomoloGene: 10823 GeneCards: SYT13
Gene location (Human)
Chromosome 11 (human)
Chr.Chromosome 11 (human)[1]
Chromosome 11 (human)
Genomic location for SYT13
Genomic location for SYT13
Band11p11.2Start45,240,302 bp[1]
End45,286,341 bp[1]
RNA expression pattern
PBB GE SYT13 221859 at fs.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_020826
NM_001247987

NM_030725

RefSeq (protein)

NP_001234916
NP_065877

NP_109650

Location (UCSC)Chr 11: 45.24 – 45.29 MbChr 2: 92.92 – 92.96 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Synaptotagmin-13 is a protein that in humans is encoded by the SYT13 gene.[5][6]

Function[edit]

SYT13 belongs to the large synaptotagmin protein family. All synaptotagmins show type I membrane topology, with an extracellular N terminus, a single transmembrane region, and a cytoplasmic C terminus containing tandem C2 domains. Major functions of synaptotagmins include vesicular traffic, exocytosis, and secretion.[supplied by OMIM][6]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000019505 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000027220 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Fukuda M, Mikoshiba K (March 2001). "Characterization of KIAA1427 protein as an atypical synaptotagmin (Syt XIII)". The Biochemical Journal. 354 (Pt 2): 249–57. doi:10.1042/0264-6021:3540249. PMC 1221650. PMID 11171101.
  6. ^ a b "Entrez Gene: SYT13 synaptotagmin XIII".

Further reading[edit]

External links[edit]

  • PDBe-KB provides an overview of all the structure information available in the PDB for Human Synaptotagmin-13 (SYT13)