SYT7

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SYT7
Protein SYT7 PDB 2d8k.png
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesSYT7, IPCA-7, IPCA7, PCANAP7, SYT-VII, SYTVII, synaptotagmin 7
External IDsMGI: 1859545 HomoloGene: 20889 GeneCards: SYT7
Gene location (Human)
Chromosome 11 (human)
Chr.Chromosome 11 (human)[1]
Chromosome 11 (human)
Genomic location for SYT7
Genomic location for SYT7
Band11q12.2Start61,515,313 bp[1]
End61,581,148 bp[1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001252065
NM_001300773
NM_004200

NM_018801
NM_173067
NM_173068

RefSeq (protein)

NP_001238994
NP_001287702
NP_004191

NP_061271
NP_775090
NP_775091

Location (UCSC)Chr 11: 61.52 – 61.58 MbChr 19: 10.39 – 10.45 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Synaptotagmin-7 is a protein that in humans is encoded by the SYT7 gene.[5][6]

Function[edit]

Synaptotagmins, such as SYT7, are brain-specific calcium-dependent phospholipid-binding proteins that play a role in synaptic exocytosis and neurotransmitter release. See MIM 600782.[supplied by OMIM][6]

Interactions[edit]

SYT7 has been shown to interact with SYNCRIP.[7]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000011347 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000024743 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". 
  4. ^ "Mouse PubMed Reference:". 
  5. ^ Cooper PR, Nowak NJ, Higgins MJ, Church DM, Shows TB (May 1998). "Transcript mapping of the human chromosome 11q12-q13.1 gene-rich region identifies several newly described conserved genes". Genomics. 49 (3): 419–29. doi:10.1006/geno.1998.5291. PMID 9615227. 
  6. ^ a b "Entrez Gene: SYT7 synaptotagmin VII". 
  7. ^ Mizutani A, Fukuda M, Ibata K, Shiraishi Y, Mikoshiba K (March 2000). "SYNCRIP, a cytoplasmic counterpart of heterogeneous nuclear ribonucleoprotein R, interacts with ubiquitous synaptotagmin isoforms". The Journal of Biological Chemistry. 275 (13): 9823–31. doi:10.1074/jbc.275.13.9823. PMID 10734137. 

Further reading[edit]