SYT9

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Synaptotagmin IX
Identifiers
Symbols SYT9 ; FLJ45896
External IDs OMIM613528 MGI1926373 HomoloGene11062 GeneCards: SYT9 Gene
RNA expression pattern
PBB GE SYT9 gnf1h06444 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 143425 60510
Ensembl ENSG00000170743 ENSMUSG00000062542
UniProt Q86SS6 Q9R0N9
RefSeq (mRNA) NM_175733 NM_021889
RefSeq (protein) NP_783860 NP_068689
Location (UCSC) Chr 11:
7.24 – 7.47 Mb
Chr 7:
107.37 – 107.55 Mb
PubMed search [1] [2]

Synaptotagmin-9 is a protein that in humans is encoded by the SYT9 gene.[1][2]

Interactions[edit]

SYT9 has been shown to interact with SYNCRIP,[3] TUBB[4] and TRPV1.[5]

References[edit]

  1. ^ Craxton M (Sep 2001). "Genomic analysis of synaptotagmin genes". Genomics 77 (1-2): 43–9. doi:10.1006/geno.2001.6619. PMID 11543631. 
  2. ^ "Entrez Gene: SYT9 synaptotagmin IX". 
  3. ^ Mizutani A, Fukuda M, Ibata K, Shiraishi Y, Mikoshiba K (Mar 2000). "SYNCRIP, a cytoplasmic counterpart of heterogeneous nuclear ribonucleoprotein R, interacts with ubiquitous synaptotagmin isoforms". The Journal of Biological Chemistry 275 (13): 9823–31. doi:10.1074/jbc.275.13.9823. PMID 10734137. 
  4. ^ Haberman Y, Grimberg E, Fukuda M, Sagi-Eisenberg R (Nov 2003). "Synaptotagmin IX, a possible linker between the perinuclear endocytic recycling compartment and the microtubules". Journal of Cell Science 116 (Pt 21): 4307–18. doi:10.1242/jcs.00719. PMID 12966166. 
  5. ^ Morenilla-Palao C, Planells-Cases R, García-Sanz N, Ferrer-Montiel A (Jun 2004). "Regulated exocytosis contributes to protein kinase C potentiation of vanilloid receptor activity". The Journal of Biological Chemistry 279 (24): 25665–72. doi:10.1074/jbc.M311515200. PMID 15066994. 

Further reading[edit]

  • Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N et al. (Oct 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514. 
  • Morenilla-Palao C, Planells-Cases R, García-Sanz N, Ferrer-Montiel A (Jun 2004). "Regulated exocytosis contributes to protein kinase C potentiation of vanilloid receptor activity". The Journal of Biological Chemistry 279 (24): 25665–72. doi:10.1074/jbc.M311515200. PMID 15066994. 
  • Haberman Y, Grimberg E, Fukuda M, Sagi-Eisenberg R (Nov 2003). "Synaptotagmin IX, a possible linker between the perinuclear endocytic recycling compartment and the microtubules". Journal of Cell Science 116 (Pt 21): 4307–18. doi:10.1242/jcs.00719. PMID 12966166. 

\* Dubois T, Howell S, Zemlickova E, Aitken A (Apr 2002). "Identification of casein kinase Ialpha interacting protein partners". FEBS Letters 517 (1-3): 167–71. doi:10.1016/S0014-5793(02)02614-5. PMID 12062430. 

  • Zhang X, Kim-Miller MJ, Fukuda M, Kowalchyk JA, Martin TF (May 2002). "Ca2+-dependent synaptotagmin binding to SNAP-25 is essential for Ca2+-triggered exocytosis". Neuron 34 (4): 599–611. doi:10.1016/S0896-6273(02)00671-2. PMID 12062043. 
  • Fukuda M, Kowalchyk JA, Zhang X, Martin TF, Mikoshiba K (Feb 2002). "Synaptotagmin IX regulates Ca2+-dependent secretion in PC12 cells". The Journal of Biological Chemistry 277 (7): 4601–4. doi:10.1074/jbc.C100588200. PMID 11751925. 
  • Mizutani A, Fukuda M, Ibata K, Shiraishi Y, Mikoshiba K (Mar 2000). "SYNCRIP, a cytoplasmic counterpart of heterogeneous nuclear ribonucleoprotein R, interacts with ubiquitous synaptotagmin isoforms". The Journal of Biological Chemistry 275 (13): 9823–31. doi:10.1074/jbc.275.13.9823. PMID 10734137. 
  • Perin MS (Oct 1996). "Mirror image motifs mediate the interaction of the COOH terminus of multiple synaptotagmins with the neurexins and calmodulin". Biochemistry 35 (43): 13808–16. doi:10.1021/bi960853x. PMID 8901523.