Sachsenhausen may refer to several places in Germany:
- Sachsenhausen (Frankfurt am Main), a city district of Frankfurt am Main, Hesse
- Sachsenhausen (Oranienburg), a city district of Oranienburg, Brandenburg
- Sachsenhausen concentration camp, a detention and extermination facility (1936–1945) in Oranienburg, Brandenburg
- Sachsenhausen (Thuringia), a municipality in the Weimarer Land, Thuringia
- Sachsenhausen (Waldeck), a city district of Waldeck, Hesse
Sachsenhausen may also refer to:
- Sachsenhausen, the German name for Săsăuş village, Chirpăr Commune, Sibiu County, Romania
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