Salidroside

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Salidroside
Salidroside.svg
Names
IUPAC name
2-(4-Hydroxyphenyl)ethyl β-D-glucopyranoside
Preferred IUPAC name
(2R,3S,4S,5R,6R)-2-(Hydroxymethyl)-6-[2-(4-hydroxyphenyl)ethoxy]oxane-3,4,5-triol
Other names
Salidroside
Rhodioloside
Tyrosol glucoside
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
ECHA InfoCard 100.224.258 Edit this at Wikidata
UNII
  • InChI=1S/C14H20O7/c15-7-10-11(17)12(18)13(19)14(21-10)20-6-5-8-1-3-9(16)4-2-8/h1-4,10-19H,5-7H2/t10-,11-,12+,13-,14-/m1/s1 ☒N
    Key: ILRCGYURZSFMEG-RKQHYHRCSA-N ☒N
  • InChI=1/C14H20O7/c15-7-10-11(17)12(18)13(19)14(21-10)20-6-5-8-1-3-9(16)4-2-8/h1-4,10-19H,5-7H2/t10-,11-,12+,13-,14-/m1/s1
    Key: ILRCGYURZSFMEG-RKQHYHRCBF
  • C1=CC(=CC=C1CCO[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)O)O)O
Properties
C14H20O7
Molar mass 300.307 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Salidroside (rhodioloside) is a glucoside of tyrosol found in the plant Rhodiola rosea.[1] It has been studied, along with rosavin, as one of the potential compounds responsible for the putative antidepressant and anxiolytic actions of this plant.[2][3] Salidroside may be more active than rosavin,[4] even though many commercially marketed Rhodiola rosea extracts are standardized for rosavin content rather than salidroside.

References[edit]

  1. ^ Mao Y, Li Y, Yao N (November 2007). "Simultaneous determination of salidroside and tyrosol in extracts of Rhodiola L. by microwave assisted extraction and high-performance liquid chromatography". Journal of Pharmaceutical and Biomedical Analysis. 45 (3): 510–5. doi:10.1016/j.jpba.2007.05.031. PMID 17628386.
  2. ^ Perfumi M, Mattioli L (January 2007). "Adaptogenic and central nervous system effects of single doses of 3% rosavin and 1% salidroside Rhodiola rosea L. extract in mice". Phytotherapy Research. 21 (1): 37–43. doi:10.1002/ptr.2013. PMID 17072830. S2CID 46232827.
  3. ^ Mattioli L, Funari C, Perfumi M (March 2009). "Effects of Rhodiola rosea L. extract on behavioural and physiological alterations induced by chronic mild stress in female rats". Journal of Psychopharmacology. 23 (2): 130–42. doi:10.1177/0269881108089872. PMID 18515456. S2CID 206489765.
  4. ^ Panossian A, Nikoyan N, Ohanyan N, Hovhannisyan A, Abrahamyan H, Gabrielyan E, Wikman G (January 2008). "Comparative study of Rhodiola preparations on behavioral despair of rats". Phytomedicine. 15 (1–2): 84–91. doi:10.1016/j.phymed.2007.10.003. PMID 18054474.