The brother of Joseph Reinach and Théodore Reinach, he was born at St Germain-en-Laye and educated at the École normale supérieure before joining the French school at Athens in 1879. He made valuable archaeological discoveries at Myrina near Smyrna in 1880-82, at Cyme in 1881, at Thasos, Imbros and Lesbos (1882), at Carthage and Meninx (1883–84), at Odessa (1893) and elsewhere. He received honours from the chief learned societies of Europe.
In 1887 he obtained an appointment at the National Museum of Antiquities at Saint-Germain-en-Laye; in 1893 he became assistant curator, and in 1902 curator of the national museums. In 1903 he became joint editor of the "Revue archéologique", and in the same year officer of the Legion of Honour. The lectures he delivered on art at the École du Louvre in 1902-3 were published by him under the title of "Apollo : histoire générale des arts plastiques professée en 1902-1903 à l'École du Louvre". These were translated into most European languages, and became a standard handbook on the subject.
Reinach's first published work was a translation of Arthur Schopenhauer's "Essay on Free Will" ("Essai sur le libre arbitre", 1877), which passed through many editions. His "Manuel de philologie classique" (1880-1884) was crowned by the French association for the study of Greek; his "Grammaire latine" (1886) received a prize from the Society of Secondary Education; "La Nécropole de Myrina" (1887), written with Edmond Pottier, and "Antiquités nationales" were crowned by the Academy of Inscriptions. He compiled an important "Répertoire de la statuaire grecque et romaine" (3 volumes, 1897–98); also "Répertoire de peintures du Moyen âge et de la Renaissance 1280-1580" (1905, etc.); "Répertoire des vases peints grecs et étrusques" (1900). In 1905 he began his "Cultes, mythes et religions"; and in 1909 he published a general sketch of the history of religions under the title of "Orpheus; histoire générale des religions" (translated into English and published as "Orpheus, a general history of religions").
He also translated from the English HC Lea's "History of the Inquisition" as "Histoire de l'Inquisition au Moyen-âge". In 1936 his updated bibliography was published — "Bibliographie de Salomon Reinach". It has been said his bibliography runs to 262 pages and includes more than ninety lengthy works and at least seven thousand articles. (Curtis, 2003) 
- Manuel de philologie classique (1880-1884).
- Grammaire latine (1886).
- La Nécropole de Myrina (1887).
- Répertoire de la Statuaire Grecque et Romaine (3 volumes, 1897–98).
- Répertoire des Vases Peints Grecs et Étrusques (1900).
- The Story of Art Throughout the Ages, 1904; English translation of Apollo: histoire générale des arts.
- Répertoire de Peintures du Moyen Âge et de la Renaissance 1280-1580 (1905...).
- Apollo: an Illustrated Manual of the History of Art Throughout the Ages Charles Scribner's and Sons, (1907).
- The so-called Asiatic Terracotta Groups, Charles Scribner's sons, (1907).
- Orpheus: A General History of Religions, W. Heinemann, (1909).
- Cults, Myths and Religions, (1912); English translation of Cultes, mythes et religions (1908).
- A Short History of Christianity, G.P. Putnam's Sons, (1922).
- This article incorporates text from a publication now in the public domain: Chisholm, Hugh, ed. (1911). Encyclopædia Britannica (11th ed.). Cambridge University Press.
- Works by Salomon Reinach at Project Gutenberg
- Works by or about Salomon Reinach at Internet Archive
- Dictionary of Art Historians Biography of Salomon Reinach