January 4, 1979
Sloyan first appeared the 2003 independent feature film My Life With Morrissey as a florist. She continued to appear in a few short films such as No Shoulder, Shamelove, and Autodoc. In 2009, she produced and starred in the short film Plus One. Sloyan has also guest-starred in several television series such as The Beast, The Forgotten, Law & Order: LA, and NCIS. She played a recurring role as a White House employee named Jeannine Locke in the first three seasons of Scandal. She also guest-starred in another ShondaLand-produced show named Private Practice in 2010. Sloyan continued to appear in smaller films, including In the Key of Eli, Tape 407, and the television movie Murder in Mexico: The Bruce Beresford-Redman Story.
In 2014, Sloyan guest-starred in four television series, including, Castle, Parks and Recreation, Hawaii Five-0, and Rizzoli & Isles. She began a recurring role in the ShondaLand-produced show Grey's Anatomy as Dr. Penelope Blake. She first appeared in the eleventh season highly critical episode "How to Save a Life", which included the death of lead character, Derek Shepherd, played by Patrick Dempsey, who had starred on the series since the beginning. She appeared again in the 12th season, including the show's 250th episode "Guess Who's Coming to Dinner", which was mostly focused on Sloyan's character.
|2003||My Life with Morrissey||Florist||Independent feature film|
|2005||No Shoulder||Bobbie||Short film|
|2009||Plus One||Lindsay||Short film, credited as producer|
|2011||In the Key of Eli||Megs|
|2013||Do You Have a Cat?||Marissa||Short film|
|2015||Murder in Mexico: The Bruce Beresford-Redman Story||Gretchen||Television movie|
|2009||The Beast||Grace Morton||Episode: "No Turning Back"|
|2009||The Forgotten||Nurse||Episode: "Railroad Jane"|
|2010||Law & Order: LA||Rachel Forester||Episode: "Echo Park"|
|2011||The Cape||Television reporter||Episode: "Endgame"|
|2011||NCIS||Emily Goodwin||1 episode|
|2012–2014||Scandal||Jeannine Locke||Recurring role (8 episodes)|
|2013||The Fosters||ER Doctor||Episode: "Vigil"|
|2014||Castle||Pam Clark||1 episode|
|2014||Parks and Recreation||Erica||Episode: "New Slogan"|
|2014||Hawaii Five-0||Sarah Richmond||1 episode|
|2014||Rizzoli & Isles||Alex Ruebens||Episode: "If You Can't Stand the Heat"|
|2015–2016||Grey's Anatomy||Dr. Penelope Blake||Recurring role|
|2015||Criminal Minds||Tracy Senarak||Episode: "The Witness"|
|2018||The Haunting of Hill House||Leigh||Recurring role|
|2018||SEAL Team||Victoria Seaver||Recurring role|
- "Samantha Sloyan". IMDb. Retrieved October 25, 2015.
- Denninger, Lindsay (October 22, 2015). "Who Plays Penny On 'Grey's Anatomy'? Samantha Sloyan Is The Hospital's Newest Resident". Bustle. Retrieved October 25, 2015.