In 1621, Eure was elected Member of Parliament for Beaumaris. He was made Kings Attorney for Wales for life on 11 April 1622 and, together with Ralph Goodwin, was granted the office of Examiner in the Court of the Marches of Wales on 19 November 1625 . In 1638 he became a Bencher of his Inn and in 1640 was elevated to Serjeant-at-law and then King's Serjeant.
In November 1640, Eure was elected MP for Leominster in the Long Parliament. and was knighted on 7 August 1641. When the Civil War was taking shape he made his way to join King Charles at Oxford and was created DCL (Doctor of Civil Law) there on 7 February 1643. He was also made Speaker of the King's Parliament in Oxford (as distinct from the de facto Parliament in Westminster). In consequence he was disabled from sitting in the House of Commons on 22 January 1644 and made to suffer, although not excessively, for his support of the King's cause. 
Eure died at his home at Gatley Park, Herefordshire in 1659.
- W R Williams The Parliamentary History of the Principality of Wales
- Browne Willis Notitia parliamentaria, or, An history of the counties, cities, and boroughs in England and Wales: ... The whole extracted from mss. and printed evidences 1750 pp 229-239
- Knights of England
- 'Alumni Oxonienses, 1500-1714: Eade-Eyton', Alumni Oxonienses 1500-1714: Abannan-Kyte (1891), pp. 440-479. Date accessed: 29 April 2011
- Roberts, Stephen. "Eure, Sir Sampson (c.1592–1659?), lawyer and politician". Oxford Dictionary of National Biography (online ed.). Oxford University Press. doi:10.1093/ref:odnb/70464. (Subscription or UK public library membership required.)
|Parliament of England|
|Member of Parliament for Beaumaris
|Member of Parliament for Leominster
With: Walter Kyrle