Issacharoff graduated from Binghamton University in 1975 and Yale Law School in 1983. Issacharoff was born in Argentina in Buenos Aires. He is currently the Bonnie and Richard Reiss Professor of Constitutional Law at New York University School of Law. His students at NYU Law commonly refer to him as "El Gaucho" because he is from Argentina and many of the hypotheticals he uses in class and in his book on Civil Procedure involve cows. He served as a visiting professor at Harvard Law School for the Fall 2008 semester. Prior to joining NYU Law's faculty, he taught at Columbia Law School and The University of Texas School of Law.
His wife, Cynthia Estlund, is a labor and employment-law professor, also at New York University School of Law.
- The Supreme Court, 2012 Term — Comment: Beyond the Discrimination Model on Voting, 127 Harv. L. Rev. 95 (2013).
- The Supreme Court, 2009 Term — Comment: On Political Corruption, 124 Harv. L. Rev. 118 (2010).
- Fragile Democracies, 120 Harv. L. Rev. 1405 (2007).
- Party Funding and Campaign Financing in International Perspective with Keith Ewing (eds.) (2006) ISBN 1-84113-570-4
- Civil Procedure (2005) ISBN 1-58778-034-8 (pbk. : alk. paper).
- The Law of Democracy: Legal Structure of the Political Process with Pamela S. Karlan, Richard H. Pildes. (1998) ISBN 1-56662-462-2 (alk. paper).
- The State of Voting Rights Law (1993).
- When Elections Go Bad: The Law of Democracy and the Presidential Election of 2000 with Pamela S. Karlan, Richard H. Pildes. Rev. ed. (2001) ISBN 1-58778-233-2 (alk. paper)
- "Gerrymandering: The Art of Redrawing Elections". Talks on Law'. Retrieved 22 November 2017.
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