Sandfly fever Naples phlebovirus

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Sandfly fever Naples phlebovirus
Virus classification e
(unranked): Virus
Realm: Riboviria
Phylum: Negarnaviricota
Class: Ellioviricetes
Order: Bunyavirales
Family: Phenuiviridae
Genus: Phlebovirus
Sandfly fever Naples phlebovirus

Sandfly fever Naples phlebovirus (SFNV) is an antigenic species of genus Phlebovirus within the family Phenuiviridae of the order Bunyavirales. It is an enveloped RNA virus with a tripartite genome e Uukuniemi (UUK) serogroup. The Sandfly group's natural reservoir are sandflies, while the natural reservoir for Uukuniemi is ticks. The SFNV serogroup consists of two main serocomplexes associated with disease in humans, the Naples and Sicilian serocomplexes. Sandfly fever induces myalgia, fever, and elevated liver enzymes in humans. It is difficult to diagnose outside endemic areas.[1][2]

Natural reservoir[edit]

Phlebotomine sandflies (Psychodidae) are the natural reservoir and transmit to humans via bite. Psychodidae has a wide geographical distribution.[3][4][5][6]


  1. ^ Nichol ST, Beaty BJ, Elliott RM, Goldbach R, Plyusnin A (2005) Genus Phlebovirus. In: Virus Taxonomy: Eighth Report of the International Committee on Taxonomy of Viruses, Faguet CM, Mayo MA, Maniloff J, Desselberger U, Ball LA, (eds.). Elsevier Academic Press 709–711.
  2. ^ Palacios G, Savji N, Travassos da Rosa A, Desai A, Sanchez-Seco MP, et al. (2013) Characterization of the Salehabad virus species complex of the genus Phlebovirus (Bunyaviridae). J Gen Virol 94: 837–842.
  3. ^ Mertz GJ (1997) Bunyaviridae: Bunyaviruses, Phleboviruses, Nairoviruses and Hantaviruses. In: Clinical Virology, Richman DD, Whitley RJ, Hayden FG, (eds.). Churchill-Livingstone, New York.
  4. ^ Guler S, Guler E, Caglayik DY, Kokoglu OF, Ucmak H, et al. (2012) A sandfly fever virus outbreak in the East Mediterranean region of Turkey. Int J Infect Dis 16: e244–246.
  5. ^ Schultze D, Korte W, Rafeiner P, Niedrig M (2012) First report of sandfly fever virus infection imported from Malta into Switzerland, October 2011. Euro Surveill 17.
  6. ^ Nissen NB, Jespersen S, Vinner L, Fomsgaard A, Laursen A (2011) Sandfly virus meningitis in a Danish traveller returning from Tuscany. Ugeskrift for Lægerer 173: 2505–2506.

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