Sandler Foundation is a charitable foundation formed in 1991 with support from Herbert Sandler and Marion Sandler. In 2006, the Sandlers made a contribution of $1.3 billion to the foundation, which was the second largest American charitable contribution of 2006. Sandler Foundation is a spend-down foundation as the Sandlers have signed The Giving Pledge. The Sandlers founded ProPublica.
Sandler Foundation's mission to "invest in strategic organizations and exceptional leaders that seek to improve the rights, opportunities and well-being of others, especially the most vulnerable and disadvantaged."
A 2008 New York Times article notes that the foundation has provided substantial support to several nonprofit organizations, including ProPublica, the Center for American Progress, the Center for Responsible Lending, Human Rights Watch, the American Civil Liberties Union, as well as other nonprofit organizations that conduct research in parasitic diseases, asthma (the American Asthma Foundation), and basic science (UCSF Program for Breakthrough Biomedical Research).
Sandler Foundation also helped establish the Human Rights Center at UC Berkeley, the Sandler Asthma Basic Research Center at UCSF, and the Sandler Center for Drug Discovery at UCSF (previously the Sandler Center for Basic Research in Parasitic Diseases).
Sandler Foundation has been identified as a supporter of other charitable work, including:
- A Johns Hopkins University national effort to reduce central-line associated bloodstream infections 
- The Pew Charitable Trusts' "Safe Credit Cards Project"
- Public Library of Science (PLoS)
- Center on Budget and Policy Priorities 
- National Center for Youth Law 
- Oceana 
- Earthjustice 
- Free Press 
- PICO National Network 
- Tax Policy Center 
In an article for Inside Philanthropy, David Callahan wrote that the foundation's strategy involved strong organizational leaders and providing long term general support. Callahan listed ProPublica and the Center for American Progress as notable funding successes for the Sandler Foundation.
- "The 60 largest American charitable contributions of the year". Slate.com. 2007-02-15. Retrieved 2013-10-18.
- Blackburn, Bradley (August 4, 2010). "The Giving Pledge: Billionaires Promise to Donate at Least Half Their Fortunes to Charity". ABC News. Retrieved 7 December 2015.
- Shafer, Jack (October 15, 2007). "What Do Herbert and Marion Sandler Want?". Slate. Retrieved 7 December 2015.
- "Our Mission". Sandler Foundation. Retrieved 7 December 2015.
- Nocera, joe (March 9, 2008). "Self-Made Philanthropists". New York Times. Retrieved 7 December 2015.
- "Human Rights Center". Hrc.berkeley.edu. 2012-12-10. Retrieved 2013-10-18.
- "Sabre Asthma Basic Research Center". Sabre.ucsf.edu. Retrieved 2013-10-18.
-  Archived June 26, 2010, at the Wayback Machine.
- "CE article: Are checklists the future of infection prevention?* - www.strategiesfornursemanagers.com © 2013". Strategiesfornursemanagers.com. Retrieved 2013-10-18.
-  Archived January 6, 2010, at the Wayback Machine.
- "About". PLOS. 2013-08-13. Retrieved 2013-10-18.
- "Donors: National Center for Youth Law". youthlaw.org. Retrieved 2013-10-18.
- "Foundation Donors". Na.oceana.org. Retrieved 2013-10-18.
- "Foundations That Support Us". Earthjustice. Retrieved 2013-10-18.
- "About PICO - PICO National Network". Piconetwork.org. Retrieved 2013-10-18.
- "TPC About Us | Funders". Taxpolicycenter.org. Retrieved 2013-10-18.
- Callahan, David (January 27, 2015). "The Sandler Way: Where Big Philanthropy Meets the Art of Common Sense". Inside Philanthropy. Retrieved February 25, 2015.