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Sandworm may refer to:
- Arenicola marina (Lugworm), called "sandworm" in the UK
- Alitta virens, formerly Nereis virens (King Ragworm), called "sandworm" in the US
- Hookworm larvae which cause cutaneous larva migrans, called "sandworms" in the southern US
- The Mongolian death worm is said to inhabit the Gobi Desert
- Sandworm (Dune), from Frank Herbert's 1965 science fiction novel Dune and its derivative works
- The Chthonians of H. P. Lovecraft's Cthulhu Mythos, first mentioned in 1968
- Purple worm, a fictional monster from the Dungeons & Dragons roleplaying game, first introduced in the games 1974 original set
- Sandworms, common threats native to the fictional desert planet Motavia in Sega's original Phantasy Star series of roleplaying video games, originating in 1987
- Sandworms, creatures featured in the 1988 film Beetlejuice and more heavily in its spin-off TV series
- The Graboids of the Tremors franchise, first introduced in 1990
|This disambiguation page lists articles associated with the title Sandworm.
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